Protein Alignment HOXA2 and zen2

DIOPT Version :10

• Sequence 1: NP_006726.1
• Gene: HOXA2 / 3199
• HGNCID: 5103
• Length: 376
• Species: Homo sapiens
• Sequence 2: NP_476794.1
• Gene: zen2 / 40827
• FlyBaseID: FBgn0004054
• Length: 252
• Species: Drosophila melanogaster
• Alignment Length: 294
• Identity: 83/294 - (28%)
• Similarity: 123/294 - (41%)
• Gaps: 65/294 - (22%)

Human    89 ALQPPEYPWMKEKKAAKKTALLPAAAAAATAAATGPACLSHKESLEIADGSGGGSRRLRTAYTNT 153
            |:|...|  ..:..:.....:.|.......||.|.....|.|            |:|.|||:::.
  Fly     3 AIQSENY--FVDNYSVSDLMMYPCVELNVEAAPTATTRSSEK------------SKRSRTAFSSL 53

Human   154 QLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKCKSL- 217
            ||:|||:|||.||||.|.||:||:..|.|||||||:||||||||.|:.|      |.:|...:|
  Fly    54 QLIELEREFHLNKYLARTRRIEISQRLALTERQVKIWFQNRRMKLKKST------NRKGAIGALT 112

Human   218 -------EDSEKVEEDEE--EKTLFEQALSVSGALLER-------EGY---TFQQNALSQQQAPN 263
                   :.||.:::|::  |:.|.....:|..|.|.:       ||.   .:|......:.:|
  Fly   113 TSIPLSSQSSEDLQKDDQIVERLLRYANTNVETAPLRQVDHGVLEEGQITPPYQSYDYLHEFSP- 176

Human   264 GHNGDSQSFPVSPLTSNEKN-LKHFQHQSPTVPNCLSTMGQNCGAGLNNDSPEALEVPSLQDFSV 327
                :..:.|..|....:.| ...:....||:|...:.:..|           ..:.|.:|:|..
  Fly   177 ----EPMALPQLPFNEFDANWASSWLGLEPTIPIAENVIEHN-----------TQDQPMIQNFCW 226

Human   328 FSTDSCLQLSDAVSPSLPGSLDSPVDISADSLDF 361
            .|..|....||.        ||...|...:.|:|
  Fly   227 DSNSSSASSSDI--------LDVDYDFIQNLLNF 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA2	NP_006726.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..93		2/3 (67%)
		Antp-type hexapeptide	94..99		1/4 (25%)
		Homeodomain	144..200	CDD:459649	37/55 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..229		8/40 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..279		3/21 (14%)
zen2	NP_476794.1	Homeodomain	44..100	CDD:459649	37/55 (67%)