Protein Alignment HOXA2 and CG34031

DIOPT Version :10

• Sequence 1: NP_006726.1
• Gene: HOXA2 / 3199
• HGNCID: 5103
• Length: 376
• Species: Homo sapiens
• Sequence 2: NP_001246894.1
• Gene: CG34031 / 3885665
• FlyBaseID: FBgn0054031
• Length: 219
• Species: Drosophila melanogaster
• Alignment Length: 225
• Identity: 49/225 - (21%)
• Similarity: 89/225 - (39%)
• Gaps: 70/225 - (31%)

Human   137 QKISSLETKLKASEEEKQRIKKDVESLMEKHSVLEKGFLKEKEQ----DAVSFQARYRELQEKHK 197
            :::||:..|| .||.:::.|:::             ||.|.:.:    .||..:..::.|
  Fly    31 RELSSVVAKL-CSEGDEELIRRE-------------GFFKRRSEFIVAGAVLLEEIFKAL----- 76

Human   198 QELEDMRKAGHEALSIIVDEYKALLQSSVKQQLDAIEKQYVSAIEKQAH-RCEELLHAQHQRLLD 261
             .:|||.          |.|| ||.:..:   .|::.|.:..:.:..|: |...::     ||..
  Fly    77 -GIEDME----------VSEY-ALAEGVI---ADSLAKAFDGSYDLNANARWRSVM-----RLAT 121

Human   262 VLDTEKELLR----EKIQEALTQQSQEQKESLEKCLQEEM---QRNKETLESAVKLEKEAMKDVI 319
            ....:|.:..    .||       ::|....|.||...::   .::.|.||:|..|....   :|
  Fly   122 RFSGKKRMTHAIHCAKI-------AKEIYLGLRKCNDFKVILDDKDLEYLEAACFLHNIG---II 176

Human   320 TKAVGEERE------NLEKVH---AEEREL 340
            |...|..::      |.:.:|   |||.||
  Fly   177 TGKKGYHKQSYHIIKNGDHLHSYTAEEIEL 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA2	NP_006726.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..93
		Antp-type hexapeptide	94..99
		Homeodomain	144..200	CDD:459649	11/59 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..229		8/30 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..279		5/25 (20%)
CG34031	NP_001246894.1	Homeodomain	134..190	CDD:459649	14/65 (22%)