Protein Alignment HOXA2 and inv

DIOPT Version :10

• Sequence 1: NP_006726.1
• Gene: HOXA2 / 3199
• HGNCID: 5103
• Length: 376
• Species: Homo sapiens
• Sequence 2: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Alignment Length: 237
• Identity: 67/237 - (28%)
• Similarity: 102/237 - (43%)
• Gaps: 32/237 - (13%)

Human    17 SLAE-CLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSHPRHGAGGRPKPSPA-- 78
            |||. |..|....:....||:..||......:..||     |:...|:....|..|....:|.
  Fly   357 SLANICSNSNDSNSTATSSSTTNTSGAPVDLVKSPP-----PAAGAGATGASGKSGEDSGTPIVW 416

Human    79 -----GSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAAATGPACLSHKESLEIADG 138
                 .:|.|..|:....|      :.:|..|     ||.:::|.....|..     |..|.|||
  Fly   417 PAWVYCTRYSDRPSSGRSP------RARKPKK-----PATSSSAAGGGGGGV-----EKGEAADG 465

Human   139 SG-GGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT 202
            .| ...:|.|||::.|||..|:.||:.|:||...||.:::..|.|.|.|:|:||||:|.|.|:.:
  Fly   466 GGVPEDKRPRTAFSGTQLARLKHEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSS 530

Human   203 QCKENQNSEGKCKSLEDSEKV--EEDEEEKTLFEQALSVSGA 242
            ..|.....:...:.|.:...:  ..:|||....::|.|.:.|
  Fly   531 GTKNPLALQLMAQGLYNHSTIPLTREEEELQELQEAASAAAA 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA2	NP_006726.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..93		10/57 (18%)
		Antp-type hexapeptide	94..99		0/4 (0%)
		Homeodomain	144..200	CDD:459649	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..229		4/32 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..279
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	26/55 (47%)
		Engrail_1_C_sig	529..554	CDD:431338	2/24 (8%)