Protein Alignment HOXA2 and cad

DIOPT Version :10

• Sequence 1: NP_006726.1
• Gene: HOXA2 / 3199
• HGNCID: 5103
• Length: 376
• Species: Homo sapiens
• Sequence 2: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Alignment Length: 277
• Identity: 71/277 - (25%)
• Similarity: 98/277 - (35%)
• Gaps: 85/277 - (30%)

Human    11 FINSQPSLAECLTSFPPVADTFQSSSIKTSTLSHSTLIP--PPFEQTIPSL-------------- 59
            |:.:.|:.|..|...........|||..:|..|.|...|  |...:|..|:
  Fly    94 FVQNVPTSAHQLMQQHHHHHAHASSSSASSGSSSSGGAPGAPQLNETNSSIGVGGAGGGGGVGGA 158

Human    60 ---NPGS----HPRHGAGGRPKP------SPAGSRGSPVPAGA---------------------- 89
               .|||    |.:|.|.|.|.|      |...|.|:|..|.:
  Fly   159 TDGGPGSAPPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVANNNNNNNNN 223

Human    90 ------------------------LQPPEYPWMKEKKAAKKTALLPAAAAAATAAATGPACLSHK 130
                                    .:||.:.|||:          ||..|......:....|...
  Fly   224 NNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKK----------PAYPAQPQPDLSSSPNLEDL 278

Human   131 ESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRR 195
            ..|..|.|......:.|..||:.|.||||||:..::|:...|:.|:|..|.|:|||||:||||||
  Fly   279 SDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRR 343

Human   196 MKHKRQTQCKENQNSEG 212
            .|.::|.:...:.|..|
  Fly   344 AKERKQNKKGSDPNVMG 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA2	NP_006726.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..93		20/125 (16%)
		Antp-type hexapeptide	94..99		1/4 (25%)
		Homeodomain	144..200	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..229		3/15 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..279
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	28/54 (52%)