DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment HOXA2 and B-H1

DIOPT Version :10

Sequence 1:NP_006726.1 Gene:HOXA2 / 3199 HGNCID:5103 Length:376 Species:Homo sapiens
Sequence 2:NP_523387.1 Gene:B-H1 / 32724 FlyBaseID:FBgn0011758 Length:544 Species:Drosophila melanogaster


Alignment Length:236 Identity:77/236 - (32%)
Similarity:97/236 - (41%) Gaps:70/236 - (29%)


- Green bases have known domain annotations that are detailed below.


Human    30 DTFQSSSIK-----TSTLSHSTLIPPPFEQTIPSLNPGS--HPRHGAGGRPKPSPAGSRGSPVP- 86
            |..::|::.     .|.|.|    |.|...|.|..:|.:  || ||..|...|: ||..|..|. 
  Fly   130 DNCEASNVAGVGVLPSALHH----PQPHPPTHPHTHPHALMHP-HGKLGHFPPT-AGGNGLNVAQ 188

Human    87 -AGALQPPEYPWMKEKKAAKKTALLPAAAAAATAAA-----------TGPACLS----------- 128
             |.|:| ..|.......||:..|...||||||.|||           .|...|:           
  Fly   189 YAAAMQ-QHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSS 252

Human   129 --HKESLEIADG--------SGGG----------------------SRRLRTAYTNTQLLELEKE 161
              |:|:.:...|        |.||                      .|:.|||:|:.||..|||.
  Fly   253 DYHEENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMSGLSKKQRKARTAFTDHQLQTLEKS 317

Human   162 FHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT 202
            |...|||....|.|:|..|||::.|||.|:||||.|.||||
  Fly   318 FERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQT 358

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HOXA2NP_006726.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 42..93 20/54 (37%)
Antp-type hexapeptide 94..99 1/4 (25%)
Homeodomain 144..200 CDD:459649 29/55 (53%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 198..229 4/5 (80%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 257..279
B-H1NP_523387.1 Homeodomain 300..356 CDD:459649 29/55 (53%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.