DRSC/TRiP Functional Genomics Resources

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Protein Alignment HOXA2 and vnd

DIOPT Version :10

Sequence 1:NP_006726.1 Gene:HOXA2 / 3199 HGNCID:5103 Length:376 Species:Homo sapiens
Sequence 2:NP_476786.2 Gene:vnd / 31003 FlyBaseID:FBgn0261930 Length:723 Species:Drosophila melanogaster


Alignment Length:230 Identity:65/230 - (28%)
Similarity:88/230 - (38%) Gaps:63/230 - (27%)


- Green bases have known domain annotations that are detailed below.


Human    14 SQPSLAECLTSFPPVADTFQSSSIKTS--------TLSHSTLIPPPFEQTIPSLNPGSHPRHGAG 70
            :.|.....:||  .|:.|:..|:.:||        :.|.|.      :....|:....|..||:.
  Fly   411 ASPDSTSPVTS--EVSYTYIGSNCQTSPALSGDYKSYSRSA------DSDALSVGDALHTLHGSS 467

Human    71 GRPKPSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAAATGPACLSHKESL-- 133
            |.      ||.|....|.||.............:.|       |.....|.:|     |.:||  
  Fly   468 GN------GSAGGAPTAHALHNNNNNTTNNNNHSLK-------AEGINGAGSG-----HDDSLNE 514

Human   134 ----------EIADGSGGG-----------SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIA 177
                      :.|||||||           .|:.|..:|..|..|||:.|...:||..|.|..:|
  Fly   515 DGIEEDIDDVDDADGSGGGDANGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLA 579

Human   178 ALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEG 212
            :|:.||..|||:||||.|.|.||.      ||.:|
  Fly   580 SLIRLTPTQVKIWFQNHRYKTKRA------QNEKG 608

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HOXA2NP_006726.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 42..93 13/50 (26%)
Antp-type hexapeptide 94..99 0/4 (0%)
Homeodomain 144..200 CDD:459649 25/55 (45%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 198..229 5/15 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 257..279
vndNP_476786.2 Homeodomain 546..602 CDD:459649 25/55 (45%)
Blue background indicates that the domain is not in the aligned region.

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