Protein Alignment CG2124 and FASTKD3

DIOPT Version :9

• Sequence 1: NP_572638.1
• Gene: CG2124 / 31989
• FlyBaseID: FBgn0030217
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_076996.2
• Gene: FASTKD3 / 79072
• HGNCID: 28758
• Length: 662
• Species: Homo sapiens
• Alignment Length: 630
• Identity: 129/630 - (20%)
• Similarity: 232/630 - (36%)
• Gaps: 175/630 - (27%)

  Fly    69 MRPQPDASAADLYADFLGLVRHCNRMELK----------ISDSRYEAFTRCFCEQLHRLTDEQLL 123
            |...||..||       |.::....:|.|          :.:|.::|....|.::..:|::..|:
Human   122 METLPDTMAA-------GALQRICEVEKKDGDQGLPKEILENSIFQALCFQFEKEPSQLSNTSLV 179

  Fly   124 GSLSALAELPV-PESPKAKNYMEIWNTLDIECCRRIERWSSE--QLLLVSDAWYRL---GLVRIG 182
            .:|.||..|.| |:|....|       |..||..|:.:...|  .|.::.::...|   |.|.:.
Human   180 TALQALILLHVDPQSSLLLN-------LVAECQNRLRKGGMEVRNLCILGESLITLHSSGCVTLE 237

  Fly   183 EYVWLALKKL-GRKLRKLPPEQLVHSMFLCNLLRRPVFEMFDFELNLARCVDQMTLSELGVMAMG 246
                |.:.:| |.||....||.:|   .|..:| :...|..|........::..:||.:..:
Human   238 ----LIINQLQGEKLETFTPEDIV---ALYRIL-QACTEKVDEHQTFLNKINNFSLSIVSNL--- 291

  Fly   247 FFKTQTPIRNPELLTQLYQRLGSELDTVEDIVLVALLKVLRYSSK-LPQV--EPLKKML------ 302
                     :|:|::|:...| ..||..:...|:  :|:.:|..: :|..  |.|:::|
Human   292 ---------SPKLISQMLTAL-VVLDQSQAFPLI--IKLGKYVVRHVPHFTNEELRRVLEAFIYF 344

  Fly   303 --------SALESQVDRVSLLTCLHMALLGCELQTCNDALVERILLRFERELETARLKDMERICL 359
                    .|||.:|..|    ||          |.:..:|.|::....|||    :.....:..
Human   345 GHHDTFFTKALEHRVAAV----CL----------TLDPEVVCRVMEYCSREL----ILSKPILNA 391

  Fly   360 VMALFNITTKSGVERRLA---------ERLP---DLLRQRIEEIL-RH-----PRCFSNCLQFLT 406
            |...|...|:....|:::         ..||   ..|.:::|.:| .|     |:.....|...:
Human   392 VAETFVCQTEKFSPRQISALMEPFGKLNYLPPNASALFRKLENVLFTHFNYFPPKSLLKLLHSCS 456

  Fly   407 MRGVYDLELLGVALEPRFLKHAYPSGLPGREYFHLDGFAR-----------LLGPEYQGALVTEK 460
            :...:.:..|....:|.||:.     |.|:| .|||..:|           |..|.|:|..:..|
Human   457 LNECHPVNFLAKIFKPLFLQR-----LQGKE-SHLDTLSRAQLTQLFLASVLECPFYKGPKLLPK 515

  Fly   461 QRQQ------------MGRNYTQYIPDRDGRFKLNNTDRILVEIRDAITMIHRPVTFKHILPQYD 513
            .:.:            :.....:|:       |:..|:.:...:..|          ..:|..|
Human   516 YQVKSFLTPCCSLETPVDSQLYRYV-------KIGLTNLLGARLYFA----------PKVLTPY- 562

  Fly   514 RCDVVLCYDRRQRKALSINGEACQDYSGEILTRKHLLGERKAADDQLVTVVIVIAGWNNVIRDKD 578
                  ||        :|:.|...|..|.:|       ...|.:|....:.:.|.|......:..
Human   563 ------CY--------TIDVEIKLDEEGFVL-------PSTANEDIHKRIALCIDGPKRFCSNSK 606

  Fly   579 RFTGQMDMKLRQLRQLGHQPLVIYWHEWRELENSADRQDFLKRRL 623
            ...|:..:|.|.|:.||:|.:.|.:||...|::..:..::|:|:|
Human   607 HLLGKEAIKQRHLQLLGYQVVQIPYHEIGMLKSRRELVEYLQRKL 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2124	NP_572638.1	RAP	565..622	CDD:214932	14/56 (25%)
FASTKD3	NP_076996.2	FAST_1	409..477	CDD:284217	12/67 (18%)
		FAST_2	493..579	CDD:285557	17/117 (15%)
		RAP	593..650	CDD:214932	14/56 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21228
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010