DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2124 and fastkd5

DIOPT Version :9

Sequence 1:	NP_572638.1	Gene:	CG2124 / 31989	FlyBaseID:	FBgn0030217	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	XP_698448.3	Gene:	fastkd5 / 569940	-ID:	-	Length:	778	Species:	Danio rerio

Alignment Length:	487	Identity:	114/487 - (23%)
Similarity:	201/487 - (41%)	Gaps:	69/487 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 ADFLGLVRHCNRMELKIS-----DSRYEAFTRCFCEQLHRLTDEQLLGSLSALAELPVPESPKAK 141
            :|....:...:::.||.:     |.|:....:.....:|..|.:|||..|.|...|.:|.|
Zfish   172 SDITSFLHKLSQIPLKDTAVVRRDPRFSMLLQYSVAIIHTFTPQQLLDILKAFVNLDLPRS---- 232

  Fly   142 NYMEIWNTLDIECCRRIERWSSEQLLLVSDAWYRLGLVRIGEYVWLALKKL----GRKLRKLPPE 202
              ..:..:.:.|.|.:....:..||||.:|.| |..:..:.:|    ||||    .:.|.::.|.
Zfish   233 --HSVLASYEAEFCEQASEMNLHQLLLAADLW-RCLVRNVPKY----LKKLYDNVSQNLNQMSPP 290

  Fly   203 QLVHSMFLCNLLRR-PVFEMFDFELNLARCVDQMTLSELGVMAMGFFKTQTPIRNPELLTQLYQR 266
            :||..:::....|. |...:...|..|.|.::::...|||.:.:|.||.||.: :...:.:|..|
Zfish   291 ELVQLIYIIGESRGCPETLVKSIESLLMRHLNELKPEELGAVCLGLFKAQTSL-SERAVQRLVDR 354

  Fly   267 LGSELDTVEDIVLVALLKVLRYS--SKLPQVEPLKKMLSALESQVDRVSLLTCLHMALLGCELQT 329
            ....:..:.|..:|.::|.||:|  ..||.:|.:...:.....|::...|   :|: :||.....
Zfish   355 SLVVVKDMSDFGIVNVMKYLRFSYLDHLPWLEAMGVEVPRRAPQMEAQGL---MHI-ILGFSALH 415

  Fly   330 CNDALVERILLRFEREL----ETARLKDMERICLVMALFNITTKSGVERRLAERLPD-------L 383
            ..|   :|:||...::|    ...|.||..::.........         |..:.||       |
Zfish   416 YRD---DRVLLAVAKQLPNVINQCRSKDAAKMLWAYGSLGF---------LPSQCPDLYPSLTAL 468

  Fly   384 LRQRIEEILRHPRCFSNCLQFLTMRGVYDLELLGVALEPRFLKHA--YPSGLPGREYFHLDGFAR 446
            ||:|..|..|.|......|..|...|::..:||.:||...|:..|  |......|:.|.|||...
Zfish   469 LRERQSEFQRFPEHLLTGLLGLAFAGLFPEDLLSLALSEEFVDRACKYQELELNRDLFTLDGTVG 533

  Fly   447 LLGPEYQGALVTEKQRQQMGRNYTQYIPDRDGRFKLNNTDRILVEIRDAITMIHRPV-----TFK 506
            |..||.....::...|:::.:....:......: ||        |:.:|.:|:.:.:     ..|
Zfish   534 LELPESTIPRLSLAVREEVTKQLWDFAQSEICQ-KL--------EVLEAESMLQKLLGGEMFVRK 589

  Fly   507 H-ILPQYDRCDVVLCYDRRQRKALSINGEACQ 537
            | |||.....|:.:..|:.. :.:|:...:||
Zfish   590 HMILPHLRSIDLEVHLDQND-QPVSVTSGSCQ 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2124	NP_572638.1	RAP	565..622	CDD:214932
fastkd5	XP_698448.3	FAST_1	442..512	CDD:284217	18/78 (23%)
		FAST_2	525..612	CDD:285557	20/96 (21%)
		RAP	712..771	CDD:214932
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D215819at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8024
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.040