Protein Alignment CG2124 and Fastkd1

DIOPT Version :10

• Sequence 1: NP_572638.1
• Gene: CG2124 / 31989
• FlyBaseID: FBgn0030217
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001178667.1
• Gene: Fastkd1 / 311112
• RGDID: 1563531
• Length: 832
• Species: Rattus norvegicus
• Alignment Length: 634
• Identity: 119/634 - (18%)
• Similarity: 228/634 - (35%)
• Gaps: 170/634 - (26%)

  Fly    83 DFLGLVRHCNRM-ELKISDSRYEAFTRCFC-----------EQL--------HRLTDEQLLGSLS 127
            :|:.:.|  .|: ||.:.....|:|.|.|.           :||        ..|:.:|.|..|.
  Rat   270 EFIEVAR--GRLAELSLPSDHPESFVRLFAALGPVARPEIRKQLKSTILLLSEELSSQQALTVLG 332

  Fly   128 ALAELPVPESPKAKNYMEIWNTLDIECCRRIERWSSEQLLLVSDAWYRLGLVRIGEYVWLALKKL 192
            |:.::...:|...|..:.:       ..|.::...|.:||.:..|.         .::....|:|
  Rat   333 AMEDMESRDSHLIKKIVSV-------LYRHLDNCKSVELLKIIQAL---------TFLHFQSKEL 381

  Fly   193 GRKLRKLPPEQLVHSMFLCNLLRRPVFEMFDFELNLARCVDQMTLSELGVMAMGFFKTQTPIRNP 257
            ..|||                           |:.|:|....:|.||:.|:.........|..|.
  Rat   382 FMKLR---------------------------EVLLSRLEASVTPSEVSVLVSALSMLPYPHLNE 419

  Fly   258 ELLTQLYQRLGS-ELDTVEDIVLVALLKVLR------YSSKLPQVEPLKKMLSALESQVDRVSLL 315
            ..|::....|.. :...:.|:| |.|::.::      .|:...|::.|:|:......::.:.:.|
  Rat   420 TALSRTETVLPQCDFRELSDLV-VCLMRWIQNDHLCSASTAGKQLDLLQKLDHWGHRRLQQSTSL 483

  Fly   316 TCLHMALLGCELQTCNDALVERILLRFERELETARLKDMERICLVMALFNITTKSGVERRLAERL 380
            ..|...|...:.:..:::|||..:...:|.::.....::.:|...::..|.     :...|.:|:
  Rat   484 DLLWEELKSVKGEWLHESLVEESITALQRFMDEIDHSNVAKIASFLSKTNY-----LSTPLLDRI 543

  Fly   381 PDLLRQRIEEILRHP-------------------------RCFSNCLQFLTMRGVYD---LELLG 417
            ..::.::|::|  ||                         .|...|..:|   |..|   |..||
  Rat   544 ASVVVEQIKKI--HPFSVLAIILPFSILNYDPPQKDEFFGACVQCCNSYL---GTLDPGTLVFLG 603

  Fly   418 VALE-----PR-FLKHAY---------------PSGLPGREYFHLDGFAR---LLGPEYQGALVT 458
            .::.     |. .||..:               ||.|..|..|.|....|   |..||.|.....
  Rat   604 FSMATLEYFPEDLLKKMFNIEFLARLDSQLEILPSSLSARIQFRLMELNRAVCLECPELQVPWFH 668

  Fly   459 EKQRQQMGRNYTQYIPDRDGRFKLNNTDRILVEIRDAITMIHRPVTFKHILPQYDRCDVVLCYDR 523
            ::..|:      |:..|..   .:|...:.:.::...:...||.|....:.|.|...|.....|:
  Rat   669 DRFCQR------QFNKDTG---VMNGAQQQIYKMLAEVLGGHRYVKPSTLSPYYHTVDFECILDK 724

  Fly   524 RQR------------KALSINGEACQDYSGEILTRKHLLGERKAADDQLVTVVIVIAGWNNVIRD 576
            |::            |:..::|::....:...|..:   .||.|     :..:.|.|..:|::..
  Rat   725 RKKPLPYESHSVTPGKSPGVHGDSNTSRAEPRLPPE---AERIA-----IEFLDVRAFCSNILHL 781

  Fly   577 KDRFTGQMDMKLRQLRQLGHQPLVIYWHEWRELENSA--DRQDFLKRRL 623
            |    |:..||.|.|..||::.:.:.:.||..:..|.  .|.|:|:.::
  Rat   782 K----GKSAMKKRHLEILGYRVIQVPYFEWNSMAMSTKDTRMDYLREQI 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2124	NP_572638.1	RESC6-like	95..>251	CDD:480594	32/174 (18%)
		RAP	565..622	CDD:214932	17/58 (29%)
Fastkd1	NP_001178667.1	RESC6-like	50..301	CDD:480594	9/32 (28%)
		RESC8-like	320..>615	CDD:467929	60/348 (17%)
		FAST_1	559..630	CDD:461999	11/73 (15%)
		FAST_2	647..730	CDD:462448	18/91 (20%)
		RAP	766..824	CDD:214932	17/61 (28%)