Protein Alignment spri and MUK1

DIOPT Version :9

• Sequence 1: NP_001259418.1
• Gene: spri / 31987
• FlyBaseID: FBgn0085443
• Length: 2043
• Species: Drosophila melanogaster
• Sequence 2: NP_015255.1
• Gene: MUK1 / 856035
• SGDID: S000005991
• Length: 612
• Species: Saccharomyces cerevisiae
• Alignment Length: 630
• Identity: 107/630 - (16%)
• Similarity: 205/630 - (32%)
• Gaps: 249/630 - (39%)

  Fly   245 PIQSHQQRILN----QRFHHQRMHHGRMSHETAAAAVPGGAGASAGSIVSCAENASKVEVIVYTT 305
            |.||.::...|    .:| .|.:|..:..:|.::.  .|...::.|..:   ||          .
Yeast    17 PNQSIRESYKNTTGGMQF-QQNLHEDQNDNERSSC--DGDENSTTGERL---EN----------N 65

  Fly   306 KSDKTLKQNMNAKDDTLRKRTSLIIVPQQVHDIEVEDEDTKKVDQTK-VRENPNRNSTASMDSCV 369
            ||....||.:   |:.|...|:|.....::.||.::|     :.|.| ||.    .|...:.|..
Yeast    66 KSPILTKQEI---DEALNTVTNLPPELSKLIDIFIDD-----LKQPKYVRP----LSVLQLSSLF 118

  Fly   370 SNTTSQSNQSSGSSSSTTSSSG---SSSGSEDAHAAYQDLQNG----------NAGQDLNSPSPV 421
            .:...:.:::|....|:.:::|   |..||....||.:.|.:|          ::|..|..|.
Yeast   119 QSFYIKFDKASFQHVSSANNNGYYFSGGGSSSFLAAKETLSSGLSGIFGRSRSSSGNSLMRPR-- 181

  Fly   422 PRCHSSSSTSSVSESTSCSSS-ADYSLREQLK-NFAN---------------------------- 456
             |..|..|..|:|.||:.:.. :...:::||| |..|
Yeast   182 -RSSSLFSNESISNSTNATQMLSPEEIKKQLKINELNNMKIEKYMELCERDVFKKILIVGTSVSS 245

  Fly   457 ---------------------RNSEGGGTIDST---------------------ARLIKGMSLPV 479
                                 |||     ::.|                     ..|||.:||..
Yeast   246 PNKMKTFKPHQLQTFKVGNLFRNS-----VEFTEYNKLLNEKILCLSKLSTMNKINLIKFLSLNN 305

  Fly   480 G---------------DQSVQSVAPALCDSL-------------------------------LSP 498
            |               :.:..|::|  |:.:                               :.|
Yeast   306 GIDPEPKFEEIKDILYEFTYHSISP--CEKIKALLKLHEIMTYSQEMSNDDYLSLLIYYIITIVP 368

  Fly   499 QEVPLGRRYAEVAQFK----------------------GHPK------------ARTSEPIPSGV 529
            :::.|...:..:.::|                      |..|            ...|:.:.:.:
Yeast   369 RDIFLNAEFIRLFRYKKKLVETESFALTNLEAALVFVEGLTKNDFSNELQDKLTVNESKILENSI 433

  Fly   530 ATPSSLDSASVDGGKSHTGNNNNI---------------NNNHNGQQSQKSQQQAGLAAKL---- 575
            ::..||.|.:....|::..|.:|:               :|:::|.::........:..|:
Yeast   434 SSRVSLPSKTAIMHKNNGNNGSNLGDIVTPTIQRPDVTRSNSYDGFRTVFDSSLKNIIGKIRSYT 498

  Fly   576 ----NVLAQSNLNNNNTTNQPGSMT----PASNRTGLDSNQNQKQNLNADSRRSSSVD---PDAD 629
                |..:.:||:::|..|.|.|.:    ..|||...:.:::..::.::.||.|:|::   .:..
Yeast   499 PPHPNNTSNNNLHSSNNLNIPRSSSQLSMELSNRDTTEMSRDGSRSTSSSSRSSASLEHGNREFT 563

  Fly   630 ADDVVDAAHGGAFEDDMQALLPK-----------CSRRSRDELSQ 663
            .|..|.|:..||.:.:.|....|           |..|...|:.|
Yeast   564 GDLTVTASINGADKKEFQKSWKKYKGYKFEDLTICELRDLFEIYQ 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spri	NP_001259418.1	SH2	716..813	CDD:301589
		VPS9	1821..1922	CDD:280383
		UBQ	1946..2026	CDD:294102
MUK1	NP_015255.1	VPS9	313..412	CDD:388595	8/100 (8%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23101
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100