DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spri and vps901

DIOPT Version :9

Sequence 1:	NP_001259418.1	Gene:	spri / 31987	FlyBaseID:	FBgn0085443	Length:	2043	Species:	Drosophila melanogaster
Sequence 2:	NP_596110.2	Gene:	vps901 / 2540886	PomBaseID:	SPBC4F6.10	Length:	571	Species:	Schizosaccharomyces pombe

Alignment Length:	427	Identity:	84/427 - (19%)
Similarity:	154/427 - (36%)	Gaps:	116/427 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  1588 PALSEDDTIVEELQSTKDGSNGSCNQ--------DTLKANRNGAGHHKLNNG--------NGNGK 1636
            |:..||.|  ::..:..:...|..|:        |:|...||....|..|:.        |...:
pombe     4 PSFHEDPT--KDESTVAEQRKGQSNEEKPLIDLNDSLDEQRNAYNEHCKNHDQQPSQQVRNMEDE 66

  Fly  1637 ANNRPKVATILRNPSMRDREVLCHPRNKMSIQSSGPGDSL------------------RAYTLQL 1683
            ||...      :..|..|:||:   ..|.|:......|::                  ..:..||
pombe    67 ANQYE------QTDSSSDQEVM---NEKQSLDKENRNDNIPHENNPGQQEINEPIFDFHMFLEQL 122

  Fly  1684 AQDPSSTFARNIENFIC-CTKESREAAPQV-VMRNMRQFMSGMKNYLVKHGEGKFHAELETARAR 1746
            ....:...|:.:::|:. .||.......|| ::|:..:|::...........|. .||::.|:
pombe   123 RSSSAEPVAKYLKSFLSEFTKRRWTVNYQVKLIRDFLKFINEKIEQYEPWASGS-QAEIDNAK-- 184

  Fly  1747 LKSDEFLNLDAMLETVMHQLVV-----------LPL-REHLYGIFVDHYQRSEDIQLL----AQN 1795
                     :.|.:.|:::|..           :|| .||...:..|.. .||.::|.    .:|
pombe   185 ---------EGMEKLVLNRLYTSLFSPEIAKSGIPLSSEHSDDVEEDRV-LSEKMELFQWITEEN 239

  Fly  1796 VRYACEREAADFGIRPTVTPPSQAALRLIANLLWRLQEAELPLDKLELFLCVISTVFDATGCPRG 1860
            :....::.::.|             .:|.|:.|.|:.:...|.||:...|.....:|...   |.
pombe   240 LDIKKQKSSSKF-------------FKLAADELRRINDYHAPRDKIICLLNCCKVIFSYL---RN 288

  Fly  1861 --QQLGADDFLPVLVYVVAKCGFVGAEIEAEFMWGLLQPTLLNGEPGYYLTALCSAVQVLKTFMA 1923
              ::..||.|:|:|::||.:..........:::.....|..|.||..|||:.|..|:..::|
pombe   289 VVKEESADMFVPILIFVVLQARPAHLVSNIQYIQRFRSPEKLTGEVMYYLSTLMGAMSFIET--- 350

  Fly  1924 SEGESGSGSLDWRSSCLPACSSVLRVIIPDECNGSLQ 1960
                     ||        |||:  .|..:|.|..::
pombe   351 ---------LD--------CSSL--TITEEEFNAQIE 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spri	NP_001259418.1	SH2	716..813	CDD:301589
		VPS9	1821..1922	CDD:280383	27/102 (26%)
		UBQ	1946..2026	CDD:294102	3/15 (20%)
vps901	NP_596110.2	VPS9	252..352	CDD:280383	27/114 (24%)
vps901	NP_596110.2	CUE	529..571	CDD:214715
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23101
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100