DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32687 and Lrr47

DIOPT Version :9

Sequence 1:	NP_001259412.1	Gene:	CG32687 / 31980	FlyBaseID:	FBgn0052687	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_001260355.1	Gene:	Lrr47 / 34449	FlyBaseID:	FBgn0010398	Length:	428	Species:	Drosophila melanogaster

Alignment Length:	368	Identity:	90/368 - (24%)
Similarity:	146/368 - (39%)	Gaps:	96/368 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 KTLDFGRMSLDLVTLEDHL----ASPQKA-------LLKSS--------GDIETMLLNHNRLVGL 62
            :||..|....|.:.|..::    |.||||       :.|.|        ..::::.:|:::||.|
  Fly   105 QTLKLGMDGKDAINLRLNINAATAIPQKAQPQVRMVISKRSEYPIKGFPRTLKSLTINNSQLVKL 169

  Fly    63 PRLLLQFGNLKILDLSSNAITTLPDAVCQLPLVTLIAKNNLLTNASLPKSLLTKMANGNGNGNA- 126
            ...:....||..||:|.|.:|.:|..:.:|||.:|...||||                 |..|.
  Fly   170 SFEICTLRNLTKLDVSGNKLTKIPSELGRLPLTSLHLGNNLL-----------------GTQNDW 217

  Fly   127 --TGGTN--STLKELNLSGNQLTHFPEQVTELRHLKYLYLGGNKISSVSKDIWKMQSLHVLSLGG 187
              ..||.  .:|.||:||||.||:||..:.                       |.:||..|:|..
  Fly   218 CWLRGTKLCQSLGELDLSGNGLTYFPPPLV-----------------------KFESLVSLNLNN 259

  Fly   188 NLISEVPEAVGSLNQLQALVLCDNLIEILPTSIARLKNLKSLLLHKNRLRHLPKDIVALKNLTEL 252
            ||:|.:|.|:..:..|:.|.:|.|.:|.||:::..|: :..|.:..|..:....|  |.:.:
  Fly   260 NLLSRLPFAIRRMKALRKLYVCSNELESLPSAVEDLR-IDLLDVWGNCFKEFNAD--AAQQM--- 318

  Fly   253 SLRDNPLVVRFVQDMALKPPTLLELAGRMVKASGQRP-GPYDIPRTLAEYLNSANCCVNPNCKGV 316
                      ::|..|...|..|.|.|.........| ....||..|.:.:..|..|   .|..:
  Fly   319 ----------YLQKAASNSPQPLWLLGARAVDKYMLPLSAGSIPAVLIDLIREAPRC---PCGEL 370

  Fly   317 FFDNRVEHI-------KFV-----DFCGKYRVPLLQYLCSSKC 347
            .:..|.|.:       ||:     .:..::::.....||.|:|
  Fly   371 CYAQRKEDLFQRVVQPKFITVKNLTYSREHQIYADVVLCDSRC 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32687	NP_001259412.1	leucine-rich repeat	72..92	CDD:275380	7/19 (37%)
		leucine-rich repeat	94..133	CDD:275380	10/43 (23%)
		LRR_8	132..190	CDD:290566	17/57 (30%)
		LRR_4	134..171	CDD:289563	11/36 (31%)
		leucine-rich repeat	134..156	CDD:275380	11/21 (52%)
		leucine-rich repeat	157..179	CDD:275380	1/21 (5%)
		leucine-rich repeat	180..202	CDD:275380	8/21 (38%)
		LRR_8	202..259	CDD:290566	12/56 (21%)
		leucine-rich repeat	203..225	CDD:275380	8/21 (38%)
		leucine-rich repeat	226..248	CDD:275380	4/21 (19%)
Lrr47	NP_001260355.1	LRR_8	154..211	CDD:290566	18/56 (32%)
		LRR_4	156..194	CDD:289563	11/37 (30%)
		leucine-rich repeat	156..178	CDD:275380	4/21 (19%)
		leucine-rich repeat	179..199	CDD:275380	7/19 (37%)
		leucine-rich repeat	201..228	CDD:275380	10/43 (23%)
		leucine-rich repeat	229..274	CDD:275380	21/67 (31%)
		leucine-rich repeat	275..298	CDD:275380	8/23 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910