DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32687 and lrrc39

DIOPT Version :9

Sequence 1:	NP_001259412.1	Gene:	CG32687 / 31980	FlyBaseID:	FBgn0052687	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_001123736.1	Gene:	lrrc39 / 100170481	XenbaseID:	XB-GENE-984701	Length:	322	Species:	Xenopus tropicalis

Alignment Length:	248	Identity:	72/248 - (29%)
Similarity:	128/248 - (51%)	Gaps:	22/248 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 REQKTLDFGRMSLDLVTLEDHLASPQKALLKSSGDIETMLLNHNRLVGLPRLLLQFGNLKILDLS 78
            :|:.:.:.||:.|.:...|.....|  .|:|.. .::...::...|..:|..::.|.||.:||||
Frog    57 KEKVSNEDGRLILRIEKEEWKTLPP--CLVKIP-QLQEWQIHRTGLTAIPTCIVYFTNLLVLDLS 118

  Fly    79 SNAITTLPDAVCQLP-LVTLIAKNNLLTNASLPKSLLTKMANGNGNGNATGGTNSTLKELNLSGN 142
            .|:||.:|..:..|. |..|:...|.:  :.:|..|               .|..:|::|:||.|
Frog   119 RNSITKIPREIGTLTNLRELLLSYNRI--SEVPAEL---------------STCESLEKLDLSVN 166

  Fly   143 Q-LTHFPEQVTELRHLKYLYLGGNKISSVSKDIWKMQSLHVLSLGGNLISEVPEAVGSLNQLQAL 206
            : ::..|.|:..|..|.:|.|..|:.:|:.:.:.::.:|..|.:|.|.:.|:|:.:..:..|..|
Frog   167 RDISDLPSQLISLARLVHLDLSMNQFASIPRTVVELPALEWLDMGSNRLKELPQDIDRMQHLHTL 231

  Fly   207 VLCDNLIEILPTSIARLKNLKSLLLHKNRLRHLPKDIVALKNLTELSLRDNPL 259
            .|..|.|..||.||..::||.:|:|..|:||.:||.:.:|.:|..::.|||||
Frog   232 WLQRNEISHLPDSIGSMRNLSTLVLCNNQLRGIPKCLQSLSSLWFVNFRDNPL 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32687	NP_001259412.1	leucine-rich repeat	72..92	CDD:275380	9/19 (47%)
		leucine-rich repeat	94..133	CDD:275380	6/38 (16%)
		LRR_8	132..190	CDD:290566	17/58 (29%)
		LRR_4	134..171	CDD:289563	13/37 (35%)
		leucine-rich repeat	134..156	CDD:275380	8/22 (36%)
		leucine-rich repeat	157..179	CDD:275380	5/21 (24%)
		leucine-rich repeat	180..202	CDD:275380	6/21 (29%)
		LRR_8	202..259	CDD:290566	23/56 (41%)
		leucine-rich repeat	203..225	CDD:275380	9/21 (43%)
		leucine-rich repeat	226..248	CDD:275380	9/21 (43%)
lrrc39	NP_001123736.1	LRR_8	87..145	CDD:290566	17/58 (29%)
		leucine-rich repeat	89..111	CDD:275380	3/21 (14%)
		LRR_RI	<110..>275	CDD:238064	55/181 (30%)
		leucine-rich repeat	112..134	CDD:275380	10/21 (48%)
		LRR_8	133..192	CDD:290566	18/75 (24%)
		leucine-rich repeat	135..157	CDD:275380	6/38 (16%)
		leucine-rich repeat	158..181	CDD:275380	8/22 (36%)
		leucine-rich repeat	182..204	CDD:275380	5/21 (24%)
		leucine-rich repeat	205..227	CDD:275380	6/21 (29%)
		LRR_8	227..284	CDD:290566	23/56 (41%)
		leucine-rich repeat	228..250	CDD:275380	9/21 (43%)
		leucine-rich repeat	251..273	CDD:275380	9/21 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910