Protein Alignment PPP4R2r and Ppp4r2

DIOPT Version :9

• Sequence 1: NP_525083.2
• Gene: PPP4R2r / 31979
• FlyBaseID: FBgn0030208
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_891984.1
• Gene: Ppp4r2 / 232314
• MGIID: 3027896
• Length: 417
• Species: Mus musculus
• Alignment Length: 458
• Identity: 127/458 - (27%)
• Similarity: 211/458 - (46%)
• Gaps: 78/458 - (17%)

  Fly     8 DEIMQILERFTDLKQKEIPKELEEYLQYVAKTGDTIFKWSSLKYLFREKLLSVIKHFNEDSPRLE 72
            :.:.:.|:.|....:||:...|:::|.:|||||:|:.:||..|..|..||..|:..|...:|...
Mouse     4 ERLQEALKDFEKRGKKEVCPVLDQFLCHVAKTGETMIQWSQFKGYFIFKLEKVMDDFRTSAPEPR 68

  Fly    73 EIPNYPNVDPFNYETMKSSLLERLDLFNAAPFTVQRLCELLIDPRKQYSRIDKFMRALEKNILVV 137
            ..|| |||:...::.||..:|:.:..||..|||:|||||||.|||:.|:..|||:|.:|||::||
Mouse    69 GPPN-PNVEYIPFDEMKERILKIVTGFNGIPFTIQRLCELLTDPRRNYTGTDKFLRGVEKNVMVV 132

  Fly   138 STIDPGRKRTESENGDSLDSVVNGDLSMEVNIDIEMENNNGNADEGSSPGAGSAGCAQKASCPRS 202
            |.:.|.   :|..|.:||:.:                  ||....|:||.............||
Mouse   133 SCVCPS---SEKNNSNSLNRM------------------NGVMFPGNSPNYTDRSNINGPGTPR- 175

  Fly   203 DDNDQPK-AKKAKLEIDGEERSEASDETDTEVATRVKNEKDEKNDNDETDSPHEAAEI-----EE 261
             ..::|| :..|.|..:|  ..|::|..|:|:..     .:||..:|.:.|..|.:.:     :.
Mouse   176 -PLNRPKLSLSAPLTTNG--LPESTDSKDSELQL-----SEEKGHSDSSASESEVSLLSPVKNKH 232

  Fly   262 PDEE-VDEADQETKTTKQPAYGSQKEGEQEESFPSSADDE-----AED-----PMVSKSIEA--- 312
            |||: |:..:.|.|..|     ..|||:..|:...:...|     ||:     |...|..|:
Mouse   233 PDEDAVESEEHEVKRLK-----FDKEGDVRETASQTVSGEVSSVRAEETETAAPPPDKDRESRTR 292

  Fly   313 ----EKELVAQEKKREEDKKVAIEPKEEI-VKKEEVVESDKPDGKVAQLGDKAVVKKSTP----P 368
                |:|...:|::.||:::..:.|:|.: .:|.:..|||          |...|.:.|.    .
Mouse   293 QHCTEEEEEEEEEEEEEEEESFMTPREMVPERKNQEKESD----------DALTVNEETSEESHQ 347

  Fly   369 ADGENQEPVKVKAENEKEEKKHAPIKTEKQDDIDSTETDDAPSAEKPAEEKIASS-ESKPKTKSE 432
            .:|....|.:..:.:|:.:.  |.......|.:::.|:...||::......:.|| ||:...:..
Mouse   348 MEGSGVSPAQTDSTSERSDS--AGASRSGSDCLETQESGGPPSSKTGESVSVPSSMESEEAAEVT 410

  Fly   433 DDP 435
            |||
Mouse   411 DDP 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPP4R2r	NP_525083.2	PPP4R2	10..292	CDD:286293	91/288 (32%)
Ppp4r2	NP_891984.1	PPP4R2	6..258	CDD:286293	91/287 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	141..417		70/317 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850038
Domainoid	1	1.000	129	1.000	Domainoid score	I5268
eggNOG	1	0.900	-	-		E1_KOG3175
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	147	1.000	Inparanoid score	I4394
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004686
OrthoInspector	1	1.000	-	-		oto94490
orthoMCL	1	0.900	-	-		OOG6_104211
Panther	1	1.100	-	-	LDO	PTHR16487
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3623
SonicParanoid	1	1.000	-	-		X3873
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.820