Protein Alignment PPP4R2r and PPP4R2

DIOPT Version :9

• Sequence 1: NP_525083.2
• Gene: PPP4R2r / 31979
• FlyBaseID: FBgn0030208
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_777567.1
• Gene: PPP4R2 / 151987
• HGNCID: 18296
• Length: 417
• Species: Homo sapiens
• Alignment Length: 500
• Identity: 138/500 - (27%)
• Similarity: 213/500 - (42%)
• Gaps: 104/500 - (20%)

  Fly     8 DEIMQILERFTDLKQKEIPKELEEYLQYVAKTGDTIFKWSSLKYLFREKLLSVIKHFNEDSPRLE 72
            :.:.:.|:.|....:||:...|:::|.:|||||:|:.:||..|..|..||..|:..|...:|...
Human     4 ERLQEALKDFEKRGKKEVCPVLDQFLCHVAKTGETMIQWSQFKGYFIFKLEKVMDDFRTSAPEPR 68

  Fly    73 EIPNYPNVDPFNYETMKSSLLERLDLFNAAPFTVQRLCELLIDPRKQYSRIDKFMRALEKNILVV 137
            ..|| |||:...::.||..:|:.:..||..|||:|||||||.|||:.|:..|||:|.:|||::||
Human    69 GPPN-PNVEYIPFDEMKERILKIVTGFNGIPFTIQRLCELLTDPRRNYTGTDKFLRGVEKNVMVV 132

  Fly   138 STIDPGRKRTESENGDSLDSVVNGDLSMEVNIDIEMENNNGNADEGSSPGAGSAGCAQKASCPRS 202
            |.:.|.   :|..|.:||:.:                  ||....|:||.............||
Human   133 SCVYPS---SEKNNSNSLNRM------------------NGVMFPGNSPSYTERSNINGPGTPR- 175

  Fly   203 DDNDQPKAK-KAKLEIDGEERSEASDETDTEVATRVKNEKDEKNDNDETDSPHEAAEI-----EE 261
             ..::||.. .|.:..:|     ..:.||::.|...:||  |||.:|.:.|..|.:.:     :.
Human   176 -PLNRPKVSLSAPMTTNG-----LPESTDSKEANLQQNE--EKNHSDSSTSESEVSSVSPLKNKH 232

  Fly   262 PDEEVDEAD-QETKTTKQPAYGSQKEGEQEESFPSSADDEAEDPMVSKSIEAEKELVAQEKKR-- 323
            |||:..||: .|.|..:     ..||||..|:...:...|....||.   |.|....:|:|.:
Human   233 PDEDAVEAEGHEVKRLR-----FDKEGEVRETASQTTSSEISSVMVG---ETEASSSSQDKDKDS 289

  Fly   324 --------EEDKKVAIEPKEEIVKKEEVVESDKPDGKVAQLGDKAVVKKSTPPADGENQEPVKVK 380
                    |||::   |.:||  ::|..:.|                           :|.:..:
Human   290 RCTRQHCTEEDEE---EDEEE--EEESFMTS---------------------------REMIPER 322

  Fly   381 AENEKEEKKHAPIKTEKQDDIDSTETDDAPSAEKPAEEKIASSESKPKTKSEDDPEAETKKSQPE 445
            ...|||......:..|..::.:..|..|...|||.......|....|.:.|..|..
Human   323 KNQEKESDDALTVNEETSEENNQMEESDVSQAEKDLLHSEGSENEGPVSSSSSDCR--------- 378

  Fly   446 KTETEAAEKSVSDEKQAAEPNAESENRNDLTTSKATEAAQESVEK 490
              |||  |...|:..:..|..:||...||   .:|||...|.:|:
Human   379 --ETE--ELVGSNSSKTGEILSESSMEND---DEATEVTDEPMEQ 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPP4R2r	NP_525083.2	PPP4R2	10..292	CDD:286293	93/288 (32%)
PPP4R2	NP_777567.1	PPP4R2	9..259	CDD:312636	93/285 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..417		82/359 (23%)
		MDN1	<198..417	CDD:331582	66/276 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	126	1.000	Domainoid score	I5467
eggNOG	1	0.900	-	-		E1_KOG3175
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	146	1.000	Inparanoid score	I4434
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004686
OrthoInspector	1	1.000	-	-		oto90907
orthoMCL	1	0.900	-	-		OOG6_104211
Panther	1	1.100	-	-	O	PTHR16487
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3873
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.860