DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2887 and DNAJB8

DIOPT Version :9

Sequence 1:	NP_572633.1	Gene:	CG2887 / 31978	FlyBaseID:	FBgn0030207	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_699161.1	Gene:	DNAJB8 / 165721	HGNCID:	23699	Length:	232	Species:	Homo sapiens

Alignment Length:	157	Identity:	58/157 - (36%)
Similarity:	76/157 - (48%)	Gaps:	39/157 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DYYKILGIQRTANDGEIRKAYHKQALRYHPDKN--KSPQAEEIFKQVAKAYEVLSDKKKRGSYD- 65
            :||::||:|.:|:..:|:|||.|.|||:|||||  ...:||:.||.|::|||||||.|||..||
Human     3 NYYEVLGVQASASPEDIKKAYRKLALRWHPDKNPDNKEEAEKKFKLVSEAYEVLSDSKKRSLYDR 67

  Fly    66 -----------------SRNDKG-TRRNTANQGSGFGDG----------TAFGSCGGGSGSGSGG 102
                             |..|.| |.||..:....|..|          :.|.|..||.|.|..|
Human    68 AGCDSWRAGGGASTPYHSPFDTGYTFRNPEDIFREFFGGLDPFSFEFWDSPFNSDRGGRGHGLRG 132

  Fly   103 GSGGGRQNNPRANFGRFFDNSESYSTF 129
            ....|        ||.|....|::|:|
Human   133 AFSAG--------FGEFPAFMEAFSSF 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2887	NP_572633.1	DnaJ	1..331	CDD:223560	58/157 (37%)
		DnaJ	4..65	CDD:278647	34/62 (55%)
		DnaJ_C	163..326	CDD:199909
DNAJB8	NP_699161.1	DnaJ	3..>106	CDD:223560	43/102 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154065
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740