DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2889 and ZK686.5

DIOPT Version :9

Sequence 1:	NP_001245615.1	Gene:	CG2889 / 31977	FlyBaseID:	FBgn0030206	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_001023030.2	Gene:	ZK686.5 / 3565160	WormBaseID:	WBGene00022795	Length:	263	Species:	Caenorhabditis elegans

Alignment Length:	288	Identity:	63/288 - (21%)
Similarity:	110/288 - (38%)	Gaps:	70/288 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 DVDVNIDELPLAAGDMDEKPLDLHNLSLLGSVLDVNVDSVEVREPIK--EQLPCEEEEDEK---P 157
            |:|:.|.:        |.|.|.::|..||.            ||.:|  ::| ||....|.   .
Worm     3 DLDIEIVD--------DIKKLHIYNEYLLN------------RETLKATKEL-CELMSHESVGCS 46

  Fly   158 CLQASDSE-----PEVTEGQPESESD-------------SSDDEPLVRLKSKMKPKRKTSARSSK 204
            |.|....|     |:.|..||:.:.|             ||.........|.:..|::.:..::.
Worm    47 CFQEFPVEKAPEMPDFTIIQPDRKFDGDNAAAVAGIFVRSSTSSSFPSASSYIAAKKRKNVDNTS 111

  Fly   205 DQGPISLQQELADLLDDGGKRRRRKAPDQRTTTESQESELQAV-----LERKPKGCSRAQLAKSY 264
            .:.|.|.:.           |:|:...:.|...:....:|..|     ::.:.:...:|...|..
Worm   112 TRKPYSYKD-----------RKRKNTEEIRNIKKKLFMDLGIVRTNCGIDNEKQDREKAMKRKVT 165

  Fly   265 EKAIASYMSASCDLCEFSAPYLSELKTHFLEVHQREYYIKC--CGKVFTRASKLMDHIRKHINP- 326
            |..:.:|    |:|||.:......|..|..:||... ||:|  |.|:|::..:...|::.|..|
Worm   166 ETIVTTY----CELCEQNFSSSKMLLLHRGKVHNTP-YIECHLCMKLFSQTIQFNRHMKTHYGPN 225

  Fly   327 -KLFT-CTICKKSLNSQDYLATHIETVH 352
             |::. |.:|.:....:..|.||.:..|
Worm   226 AKIYVQCELCDRQFKDKQSLRTHWDVSH 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2889	NP_001245615.1	zf-AD	2..79	CDD:285071
		C2H2 Zn finger	276..297	CDD:275368	6/20 (30%)
		C2H2 Zn finger	306..323	CDD:275368	4/16 (25%)
		C2H2 Zn finger	331..352	CDD:275368	5/20 (25%)
		C2H2 Zn finger	366..386	CDD:275368
		C2H2 Zn finger	395..416	CDD:275368
		C2H2 Zn finger	424..444	CDD:275368
		C2H2 Zn finger	481..502	CDD:275368
		C2H2 Zn finger	510..530	CDD:275368
		C2H2 Zn finger	538..556	CDD:275368
ZK686.5	NP_001023030.2	C2H2 Zn finger	173..194	CDD:275368	6/20 (30%)
		C2H2 Zn finger	201..221	CDD:275368	5/19 (26%)
		zf-C2H2_8	<204..251	CDD:292531	12/46 (26%)
		C2H2 Zn finger	232..248	CDD:275368	3/15 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166818
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000909
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.930