DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2889 and Zfp652

DIOPT Version :9

Sequence 1:NP_001245615.1 Gene:CG2889 / 31977 FlyBaseID:FBgn0030206 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_963903.2 Gene:Zfp652 / 268469 MGIID:2442221 Length:608 Species:Mus musculus


Alignment Length:469 Identity:112/469 - (23%)
Similarity:177/469 - (37%) Gaps:92/469 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   127 GSVLDVNVDSVEVREPIKEQLPCEEEEDEKPCLQASDSEPEV-TEGQPESESDSSDDEPLVRLK- 189
            ||...|..|:       |...|...|.:|:|..:...:..:| |..:....||.:::|..|..| 
Mouse    56 GSPYSVLADT-------KMSKPHLHETEEQPYFREPRAVSDVHTVKEDRENSDDTEEEEEVSYKR 113

  Fly   190 --------------------------SKMKPKRKTSARSSKDQGPISLQQELADLLDDGGKRRRR 228
                                      ||..|..|||:...:::    .::|..|...|.|:..|:
Mouse   114 EQIIVEVNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEDEEE----TEEEATDNSSDYGENGRQ 174

  Fly   229 KAPDQRTTTESQESELQAVLERKPKGCSRAQLAKSYEKAIASYMSASCDLCEFSAPYLSELKTHF 293
            |                    :|.|...|.::.:...:..||..:|:..    .||..:..:...
Mouse   175 K--------------------KKEKQVERVRVTQRRTRRAASAAAATTS----PAPRTTRGRRKS 215

  Fly   294 LEVHQREYYIKCCGKVFTRASKLMDHIRKHINPKLFTCTICKKSLNSQDYLATHIETVHNKVAQI 358
            .|:.:|:       |..|:.:|......|....:..||..|.:..|::.||..|:...|.:: ||
Mouse   216 AELPKRK-------KRATKEAKAPVQKAKCEEKETLTCEKCPRVFNTRWYLEKHMNVTHRRM-QI 272

  Fly   359 GKVLKFPCPKCERTFSSERRMANHLAKHDTD-QLEHTCEICCKSFANVHRLRRHIQSIHEDLH-R 421
                   |.||.:.|..|..::.|   ..|| :....|..|.|||..:..|..||:.:|.... :
Mouse   273 -------CDKCGKKFVLESELSLH---QQTDCEKNIQCVSCNKSFKKLWSLHEHIKIVHGYAEKK 327

  Fly   422 HVCDICGKKFKFKPSFERHLLEHQGVVAPAVECPICRVWLKNEHSLRLHRFTHDSTDTV-CPHCG 485
            ..|:||.|||.......:|::.|...:  ...|..|....|...||::|...|...... |.:|.
Mouse   328 FACEICEKKFYTMAHVRKHMVAHTKDM--PFTCETCGKSFKRSMSLKVHSLQHSGEKPFRCENCD 390

  Fly   486 KTCTSRTALRGH--VKYAHKLTTNLQCTFCEKTFKQQRNLDEHMAIHTGLQLYNCPHCPKECRSR 548
            :....:..||.|  :...||   ...|.:|.|.|..::..||||..|||.:.:.|..|.|...||
Mouse   391 ERFQYKYQLRSHMSIHIGHK---QFMCQWCGKDFNMKQYFDEHMKTHTGEKPFICEICGKSFTSR 452

  Fly   549 SNMYVHIKQRHADE 562
            .||..| ::.|..|
Mouse   453 PNMKRH-RRTHTGE 465

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2889NP_001245615.1 zf-AD 2..79 CDD:285071
C2H2 Zn finger 276..297 CDD:275368 3/20 (15%)
C2H2 Zn finger 306..323 CDD:275368 3/16 (19%)
C2H2 Zn finger 331..352 CDD:275368 6/20 (30%)
C2H2 Zn finger 366..386 CDD:275368 6/19 (32%)
C2H2 Zn finger 395..416 CDD:275368 8/20 (40%)
C2H2 Zn finger 424..444 CDD:275368 7/19 (37%)
C2H2 Zn finger 481..502 CDD:275368 5/22 (23%)
C2H2 Zn finger 510..530 CDD:275368 8/19 (42%)
C2H2 Zn finger 538..556 CDD:275368 8/17 (47%)
Zfp652NP_963903.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 61..232 39/212 (18%)
C2H2 Zn finger 246..265 CDD:275368 6/18 (33%)
C2H2 Zn finger 273..292 CDD:275368 6/21 (29%)
C2H2 Zn finger 300..320 CDD:275368 8/19 (42%)
C2H2 Zn finger 330..350 CDD:275368 7/19 (37%)
C2H2 Zn finger 358..378 CDD:275368 6/19 (32%)
C2H2 Zn finger 386..406 CDD:275368 5/19 (26%)
C2H2 Zn finger 414..434 CDD:275368 8/19 (42%)
zf-H2C2_2 426..451 CDD:290200 10/24 (42%)
COG5048 438..>487 CDD:227381 10/29 (34%)
C2H2 Zn finger 442..462 CDD:275368 8/20 (40%)
zf-H2C2_2 454..477 CDD:290200 5/13 (38%)
C2H2 Zn finger 470..486 CDD:275368
Mediates interaction with CBFA2T3. /evidence=ECO:0000250 497..608
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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