DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2889 and zfp-2

DIOPT Version :9

Sequence 1:	NP_001245615.1	Gene:	CG2889 / 31977	FlyBaseID:	FBgn0030206	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_496055.1	Gene:	zfp-2 / 174505	WormBaseID:	WBGene00009448	Length:	422	Species:	Caenorhabditis elegans

Alignment Length:	187	Identity:	54/187 - (28%)
Similarity:	78/187 - (41%)	Gaps:	21/187 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   393 HTCEICCKSFANVHRLRRHIQSIHEDLHRHVCDICGKKFKFKPSFERHLLEHQGVVAPAVECPIC 457
            :.|..|...|.|....:||||.:|.|.....|..||.:|..|.|...||.:| .::.|...|..|
Worm   171 YRCTNCKTYFGNKEVYQRHIQEVHGDARPFRCFNCGMRFANKTSMTHHLKDH-SLLKPMFSCDYC 234

  Fly   458 -RVWLKNEHSLRLHRFTHDSTDTVCPHCGKTCTSRTALRGHVKYAHKLT---------------- 505
             |::.|.|...|.|:.  ..|.:.|..|.:..|:..|||.|...||..|
Worm   235 PRIFSKLESKTRHHKM--HFTRSTCQTCMRFFTTEDALRHHQSTAHPATFDSGPPPEDLLPNGKS 297

  Fly   506 TNLQCTFCEKTFKQQRNLDEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADE 562
            ....|::|...|..::::..|..||||.:.|:|.:|.|.......:..||: .|..|
Worm   298 ARYSCSYCNLRFHFKKDMLVHERIHTGEKPYSCGYCMKSFAQSQALTAHIR-THTKE 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2889	NP_001245615.1	zf-AD	2..79	CDD:285071
		C2H2 Zn finger	276..297	CDD:275368
		C2H2 Zn finger	306..323	CDD:275368
		C2H2 Zn finger	331..352	CDD:275368
		C2H2 Zn finger	366..386	CDD:275368
		C2H2 Zn finger	395..416	CDD:275368	8/20 (40%)
		C2H2 Zn finger	424..444	CDD:275368	8/19 (42%)
		C2H2 Zn finger	481..502	CDD:275368	7/20 (35%)
		C2H2 Zn finger	510..530	CDD:275368	4/19 (21%)
		C2H2 Zn finger	538..556	CDD:275368	4/17 (24%)
zfp-2	NP_496055.1	C2H2 Zn finger	173..194	CDD:275368	8/20 (40%)
		C2H2 Zn finger	202..222	CDD:275368	8/19 (42%)
		C2H2 Zn finger	231..251	CDD:275368	7/21 (33%)
		COG5048	<251..>358	CDD:227381	27/104 (26%)
		C2H2 Zn finger	257..278	CDD:275368	7/20 (35%)
		C2H2 Zn finger	302..322	CDD:275368	4/19 (21%)
		C2H2 Zn finger	330..350	CDD:275368	5/20 (25%)
		C2H2 Zn finger	358..374	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000