Protein Alignment Atp10b and CG33298

DIOPT Version :10

• Sequence 1: NP_795973.2
• Gene: Atp10b / 319767
• MGIID: 2442688
• Length: 1474
• Species: Mus musculus
• Sequence 2: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Alignment Length: 1452
• Identity: 563/1452 - (38%)
• Similarity: 808/1452 - (55%)
• Gaps: 255/1452 - (17%)

Mouse     9 WLRWK------WRTQDGFSQS------PSETTPLLSPETDRQSHNTAEQRVVYPNNSMCHQDWKK 61
            |  ||      :.|.|.|.:.      |:.|.|   |:|.::.|         ||.
  Fly   207 W--WKRLTLCNYNTGDKFEERSYRTVVPNHTVP---PKTPKRDH---------PNG--------- 248

Mouse    62 VCRRYPGNSICTTKYTLLTFLPQNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITIFPLATVL 126
               ::.||.|.|||||||:|:|:||.|||||.|||||:|:|:|||:|.:..|.:|:.:.|:..||
  Fly   249 ---QFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVL 310

Mouse   127 LIIMVKDGIEDFKRYCFDREMNSASIQIYERKEQRYMLKRWQDVRVGDFVQMQCNEIVPADILLL 191
            .:..|||..||.:|...|:.:|:.:.::|:.:.:||...:||::||||.|.:..||.||||||||
  Fly   311 GVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLL 375

Mouse   192 FSSDPSGVCHLETANLDGETNLKQRRVVKGFSQPEVQFQPEHFHSTIVCEKPNNHLSKFKGYMEH 256
            .:|||.|||:::|.:||||||||:|.||:||.:.:..|.|..|.|.:..:.|...|.:|.|.:.|
  Fly   376 RTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSKFVSRVEADAPTTKLYRFHGALIH 440

Mouse   257 PDQTRTGFGSESLLLRGCTIRNTEVAAGIVIYAGHETKAMLNNSGPRYKRSKIERRINTDIFFCI 321
            |...|....:|.||||...::||:...|||:|||||||:||||||||||||::|:::|.|:.:|:
  Fly   441 PTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCV 505

Mouse   322 GLLFLMCLIGAVGHSLWNGTFKEHPPFDVPDADGNFLSLALGGFYMFLTMIILLQVLIPISLYVS 386
            .:|.::|::||:|..:|..:|...|   ||....|.|:..:...::|.|.|::|||:||:||||:
  Fly   506 IILLILCVVGAIGCRMWLSSFTHFP---VPYLPPNKLTANMESMWIFWTYIVILQVMIPLSLYVT 567

Mouse   387 IELVKLGQVFLLHNDLDLYDEETDLSIQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIV 451
            |||.|:.|||.:||::||:|.||:...:|||:||||:|||||:||:|||||||||||:||||.:.
  Fly   568 IELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVN 632

Mouse   452 GSEYCHQENAKRLEMPKELDSDGEEWTQYQCLSFPPRWAQGSTTMRSQGGAQPLRRCHSARVPIQ 516
            ||:|.|.        |.||:.                       :.|:.||
  Fly   633 GSDYNHP--------PSELEK-----------------------IYSKPGA-------------- 652

Mouse   517 SHCRQRSVGRWETSQPPVAFSSSIEKDVTPDKNLLSKVRDAALWLETSDTRPAKPSHSTTASIAD 581
                         ..||          :.|:.||.|.:  |.|...|..|..|:       .|.:
  Fly   653 -------------PAPP----------LIPNDNLNSDM--AQLTQGTYLTPHAQ-------RIQE 685

Mouse   582 FFLALTICNSVMVSTTTEPRK------------RVTTPPANKALGTSLEKIQQLFQRLKLLSLSQ 634
            |.:.|.|||:|:|...  |.:            ::...|||...|.         ||.|||:.|.
  Fly   686 FLVVLAICNTVIVGAA--PHRDMMNASGIIEVQQIGNSPANLKHGK---------QRQKLLASST 739

Mouse   635 SFSSTA---------------PSD--TDLGESLG------PNL----------PTID-------- 658
            |.::|.               |:|  ..|.||..      |||          ||:.
  Fly   740 STTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPISSSAES 804

Mouse   659 --SDEKDDTSVCSGDCSTDGGYRSSTWEQGDILGSESGTSLEEGLEAPT---------------- 705
              :.|.:..|....:.|..... |.|.....::.|:. ||:...|.|.|
  Fly   805 SPNSESESPSPPMKNKSLSNSI-SPTGRAKAVINSKI-TSIATFLNAKTQGKRMKLPSSKTGTIY 867

Mouse   706 -LSQDEPELCYEAESPDEAALVHAARAYSFTLVSRTPEQVTVRLPQ-GICLTFDLLFTLGFDSVR 768
             .:...|  .||||||||.|||:||.:|...|::|:|.|:.|.:|. |....:::|..|.|||.|
  Fly   868 RTADGRP--LYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSR 930

Mouse   769 KRMSVVVRHPLTDEIIVYTKGADSVIMDLLEDPACESNIDVEKKLKRIRARTQKHLDLYARDGLR 833
            |.||:|||...:.||::|||||||.||.:|...:..|...:      :|.:||:.||.|||:|||
  Fly   931 KCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGI------LREQTQQLLDRYAREGLR 989

Mouse   834 TLCIAKKVVDEEDFQRWASFRREAEASLDNREELLMETAQHLENHLTLLGATGIEDRLQEGVPDT 898
            .|.:||:.::..|:..|.:..:|.|.||:|||..|.::...||::||||||||||||||:|||:|
  Fly   990 ILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPET 1054

Mouse   899 IAALREAGIQLWVLTGDKQETAVNIAYSCKLLDQTDTVYSINTENQETCESILNCTLEDIKRFHE 963
            ||:|..|||.:|||||||.|||:|||||.||..|...:..:...:::..|:.:|..|.|::....
  Fly  1055 IASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDMENDKT 1119

Mouse   964 PQ-----QPARKLCGHRIPPKMPSVNSGAMAPEIGLVIDGKTLNAIF--QGKLENKFLELTQYCR 1021
            ..     |..||                   .:..||:|||||..|.  :.||...||.|::.|.
  Fly  1120 TSTLGYGQSLRK-------------------KQRALVVDGKTLTFILDPKSKLILPFLRLSKRCA 1165

Mouse  1022 SVLCCRSTPLQKSMIVKLVRDKLSVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAI 1086
            ||||||||||||:.:||:|:::|::.||:||||||||||||.||:|:||||||||||||::||.:
  Fly  1166 SVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTL 1230

Mouse  1087 ARFSHLKKLLLVHGHWCYSRLARMVVYYFYKNVCYVNLLFWYQFFCGFSGSTMIDYWQMIFFNLF 1151
            .||.:|::|||.||:|||.||:||::|:||||..:|.|:||||.:|||||..|:|...::.:||.
  Fly  1231 PRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLI 1295

Mouse  1152 FTSLPPIIFGVLDKDVSAETLLALPELYKSGQNSECYNLPTFWVSMADAFYQSLICFFIPYLTYR 1216
            ||||||:..||.||.|:.:.||..|.|||:|:....|....||:.:.||.||||:.||:....|.
  Fly  1296 FTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYA 1360

Mouse  1217 GSDIDVFTFGTPINTISLTTILLHQAMEMKTWTVLHGLVLLGSFLMYFVVSLIYNATCVTCNSPT 1281
            .||:.::.|||.|....|...|:|.|:|:::|||||.|.::.|...:::.:::|::.|:.|....
  Fly  1361 ESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFAIVYDSVCMNCFGVR 1425

Mouse  1282 NPYWVMERQLSDPTFYLICLLTPVVALLPRYFLLSLQGTYGKSLISKAQKIDKLPIDKRNLEIQN 1346
            :.|||:....:....:|:.:|:.|||:|||..|.::             :|...|.|...:.:|:
  Fly  1426 SSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTV-------------RISLCPDDSTKVILQS 1477

Mouse  1347 WRSKQRPAPA----SASASASA 1364
            .|.:.|....    |.|.|||:
  Fly  1478 KRERSRGEALLVTWSRSTSASS 1499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atp10b	NP_795973.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..43		7/29 (24%)
		P-type_ATPase_APLT_Dnf-like	68..1211	CDD:319770	504/1222 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	638..707		22/128 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1348..1421		7/21 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1434..1474
CG33298	NP_995666.1	P-type_ATPase_APLT_Dnf-like	252..1355	CDD:319770	504/1222 (41%)