Protein Alignment RabX2 and RAB11B

DIOPT Version :10

• Sequence 1: NP_572627.1
• Gene: RabX2 / 31971
• FlyBaseID: FBgn0030200
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: NP_004209.2
• Gene: RAB11B / 9230
• HGNCID: 9761
• Length: 218
• Species: Homo sapiens
• Alignment Length: 194
• Identity: 70/194 - (36%)
• Similarity: 115/194 - (59%)
• Gaps: 13/194 - (6%)

  Fly     4 FDYLFKVLVLGDSGVGKSCLLMRFSDDRFTEKYLRTMGIDVKARSVELVSRVMMLQVWDTSGDKR 68
            :||||||:::||||||||.||.||:.:.|..:...|:|::...||:::..:.:..|:|||:|.:|
Human     8 YDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQER 72

  Fly    69 FNSLMPSNYRSAHGILLVYDITSSKSFQNIDGWMKEIRRMCPDKVTVLLVGNKSDDPNHRQVSME 133
            :.::..:.||.|.|.||||||....:::|::.|:||:|......:.::|||||||..:.|.|..:
Human    73 YRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTD 137

  Fly   134 QGFNYAHRGALGFEEVSAKSGMNVYDIFSSLAMDIYHRYVLHNPISPMPSEQEEEDAA---ESP 194
            :...:|.:..|.|.|.||....||.:.|.::..:||.          :.|:::..|.|   |||
Human   138 EARAFAEKNNLSFIETSALDSTNVEEAFKNILTEIYR----------IVSQKQIADRAAHDESP 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX2	NP_572627.1	Rab	8..165	CDD:206640	59/156 (38%)
RAB11B	NP_004209.2	Rab11_like	9..173	CDD:206660	62/163 (38%)
		Switch 1. /evidence=ECO:0000305|PubMed:16545962, ECO:0007744|PDB:2F9L, ECO:0007744|PDB:2F9M	36..47		3/10 (30%)
		Switch 2. /evidence=ECO:0000305|PubMed:16545962, ECO:0007744|PDB:2F9L, ECO:0007744|PDB:2F9M	67..86		6/18 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	184..218		4/8 (50%)