DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX2 and RAB33B

DIOPT Version :9

Sequence 1:	NP_572627.1	Gene:	RabX2 / 31971	FlyBaseID:	FBgn0030200	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	XP_011530601.1	Gene:	RAB33B / 83452	HGNCID:	16075	Length:	277	Species:	Homo sapiens

Alignment Length:	191	Identity:	62/191 - (32%)
Similarity:	110/191 - (57%)	Gaps:	5/191 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LFKVLVLGDSGVGKSCLLMRFSDDRFTEKYLRTMGIDVKARSVELVSRVMMLQVWDTSGDKRF-N 70
            :||::|:|||.|||:||..||...||.::...|:|:|.:.|:||:....:.:|:|||:|.:|| .
Human    81 IFKIIVIGDSNVGKTCLTYRFCAGRFPDRTEATIGVDFRERAVEIDGERIKIQLWDTAGQERFRK 145

  Fly    71 SLMPSNYRSAHGILLVYDITSSKSFQNIDGWMKEIRR-MCPDKVTVLLVGNKSDDPNHRQVSMEQ 134
            |::...||:.|.::.|||:|:..||.::..|::|.:: :..:.:..:|||||.|..:..||..:.
Human   146 SMVQHYYRNVHAVVFVYDMTNMASFHSLPSWIEECKQHLLANDIPRILVGNKCDLRSAIQVPTDL 210

  Fly   135 GFNYAHRGALGFEEVSAKSGMNVYDIFSSLAMDIYHRYVLHNPISPMPSEQEEEDAAESPD 195
            ...:|...::...|.|||: .|..|...::.|.:.|:...|.|:  |.|:..:......|:
Human   211 AQKFADTHSMPLFETSAKN-PNDNDHVEAIFMTLAHKLKSHKPL--MLSQPPDNGIILKPE 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX2	NP_572627.1	RAB	8..171	CDD:197555	56/164 (34%)
RabX2	NP_572627.1	Rab	8..165	CDD:206640	55/158 (35%)
RAB33B	XP_011530601.1	Rab33B_Rab33A	80..249	CDD:133315	57/168 (34%)
RAB33B	XP_011530601.1	RAB	82..248	CDD:197555	57/166 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810