Protein Alignment RabX2 and RAB1B

DIOPT Version :10

• Sequence 1: NP_572627.1
• Gene: RabX2 / 31971
• FlyBaseID: FBgn0030200
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: NP_112243.1
• Gene: RAB1B / 81876
• HGNCID: 18370
• Length: 201
• Species: Homo sapiens
• Alignment Length: 168
• Identity: 78/168 - (46%)
• Similarity: 113/168 - (67%)
• Gaps: 0/168 - (0%)

  Fly     4 FDYLFKVLVLGDSGVGKSCLLMRFSDDRFTEKYLRTMGIDVKARSVELVSRVMMLQVWDTSGDKR 68
            :|||||:|::|||||||||||:||:||.:||.|:.|:|:|.|.|::||..:.:.||:|||:|.:|
Human     5 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 69

  Fly    69 FNSLMPSNYRSAHGILLVYDITSSKSFQNIDGWMKEIRRMCPDKVTVLLVGNKSDDPNHRQVSME 133
            |.::..|.||.||||::|||:|..:|:.|:..|::||.|...:.|..||||||||....:.|...
Human    70 FRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDNT 134

  Fly   134 QGFNYAHRGALGFEEVSAKSGMNVYDIFSSLAMDIYHR 171
            ....:|....:.|.|.|||:..||...|.::|.:|..|
Human   135 TAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEIKKR 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX2	NP_572627.1	Rab	8..165	CDD:206640	72/156 (46%)
RAB1B	NP_112243.1	Rab1_Ypt1	7..172	CDD:206661	76/164 (46%)
		Switch 1. /evidence=ECO:0000269|PubMed:20064470, ECO:0007744|PDB:3JZA	30..45		7/14 (50%)
		Switch 2 region, required for interaction with REP1/CHM	64..83		8/18 (44%)
		Switch 2. /evidence=ECO:0000269|PubMed:20064470, ECO:0007744|PDB:3JZA	65..80		5/14 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..201