DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RabX2 and Rab1b

DIOPT Version :9

Sequence 1:	NP_572627.1	Gene:	RabX2 / 31971	FlyBaseID:	FBgn0030200	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_083852.1	Gene:	Rab1b / 76308	MGIID:	1923558	Length:	201	Species:	Mus musculus

Alignment Length:	168	Identity:	78/168 - (46%)
Similarity:	113/168 - (67%)	Gaps:	0/168 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FDYLFKVLVLGDSGVGKSCLLMRFSDDRFTEKYLRTMGIDVKARSVELVSRVMMLQVWDTSGDKR 68
            :|||||:|::|||||||||||:||:||.:||.|:.|:|:|.|.|::||..:.:.||:|||:|.:|
Mouse     5 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 69

  Fly    69 FNSLMPSNYRSAHGILLVYDITSSKSFQNIDGWMKEIRRMCPDKVTVLLVGNKSDDPNHRQVSME 133
            |.::..|.||.||||::|||:|..:|:.|:..|::||.|...:.|..||||||||....:.|...
Mouse    70 FRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDNT 134

  Fly   134 QGFNYAHRGALGFEEVSAKSGMNVYDIFSSLAMDIYHR 171
            ....:|....:.|.|.|||:..||...|.::|.:|..|
Mouse   135 TAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEIKKR 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX2	NP_572627.1	RAB	8..171	CDD:197555	74/162 (46%)
RabX2	NP_572627.1	Rab	8..165	CDD:206640	72/156 (46%)
Rab1b	NP_083852.1	Rab1_Ypt1	7..172	CDD:206661	76/164 (46%)
		Effector region. /evidence=ECO:0000255	37..45		3/7 (43%)
		Switch 2 region, required for interaction with REP1/CHM. /evidence=ECO:0000250\|UniProtKB:Q9H0U4	64..83		8/18 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	174..201
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1149105at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820