DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX2 and RAB13

DIOPT Version :9

Sequence 1:	NP_572627.1	Gene:	RabX2 / 31971	FlyBaseID:	FBgn0030200	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_002861.1	Gene:	RAB13 / 5872	HGNCID:	9762	Length:	203	Species:	Homo sapiens

Alignment Length:	165	Identity:	83/165 - (50%)
Similarity:	112/165 - (67%)	Gaps:	0/165 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FDYLFKVLVLGDSGVGKSCLLMRFSDDRFTEKYLRTMGIDVKARSVELVSRVMMLQVWDTSGDKR 68
            :|:|||:|::|||||||:||::||::|.|...|:.|:|||.|.|:|::..:.:.||||||:|.:|
Human     5 YDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTAGQER 69

  Fly    69 FNSLMPSNYRSAHGILLVYDITSSKSFQNIDGWMKEIRRMCPDKVTVLLVGNKSDDPNHRQVSME 133
            |.::..:.||.|.||:||||||..|||:||..|||.|:......|..||:|||.|....|:|..|
Human    70 FKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRKVQKE 134

  Fly   134 QGFNYAHRGALGFEEVSAKSGMNVYDIFSSLAMDI 168
            |....|....:.|.|.||||.|||.:.|||||.||
Human   135 QADKLAREHGIRFFETSAKSSMNVDEAFSSLARDI 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX2	NP_572627.1	RAB	8..171	CDD:197555	81/161 (50%)
RabX2	NP_572627.1	Rab	8..165	CDD:206640	77/156 (49%)
RAB13	NP_002861.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	83/164 (51%)
		Effector region. /evidence=ECO:0000250	37..45		4/7 (57%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	173..203
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910