Protein Alignment RabX2 and RAB6A

DIOPT Version :10

• Sequence 1: NP_572627.1
• Gene: RabX2 / 31971
• FlyBaseID: FBgn0030200
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: NP_002860.2
• Gene: RAB6A / 5870
• HGNCID: 9786
• Length: 208
• Species: Homo sapiens
• Alignment Length: 158
• Identity: 66/158 - (41%)
• Similarity: 98/158 - (62%)
• Gaps: 0/158 - (0%)

  Fly     8 FKVLVLGDSGVGKSCLLMRFSDDRFTEKYLRTMGIDVKARSVELVSRVMMLQVWDTSGDKRFNSL 72
            ||::.||:..|||:.|:.||..|.|...|..|:|||..::::.|..|.:.||:|||:|.:||.||
Human    14 FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQERFRSL 78

  Fly    73 MPSNYRSAHGILLVYDITSSKSFQNIDGWMKEIRRMCPDKVTVLLVGNKSDDPNHRQVSMEQGFN 137
            :||..|.:...::|||||:..|||....|:.::|......|.::|||||:|..:.||||:|:|..
Human    79 IPSYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGER 143

  Fly   138 YAHRGALGFEEVSAKSGMNVYDIFSSLA 165
            .|....:.|.|.|||:|.||..:|..:|
Human   144 KAKELNVMFIETSAKAGYNVKQLFRRVA 171

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX2	NP_572627.1	Rab	8..165	CDD:206640	65/156 (42%)
RAB6A	NP_002860.2	Rab6	14..174	CDD:206654	66/158 (42%)
		Switch 1. /evidence=ECO:0000269|PubMed:19141279, ECO:0007744|PDB:3CWZ	32..50		8/17 (47%)
		Switch 2. /evidence=ECO:0000269|PubMed:19141279, ECO:0007744|PDB:3CWZ	69..88		9/18 (50%)