DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX2 and RAB8A

DIOPT Version :9

Sequence 1:	NP_572627.1	Gene:	RabX2 / 31971	FlyBaseID:	FBgn0030200	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_005361.2	Gene:	RAB8A / 4218	HGNCID:	7007	Length:	207	Species:	Homo sapiens

Alignment Length:	165	Identity:	78/165 - (47%)
Similarity:	112/165 - (67%)	Gaps:	0/165 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FDYLFKVLVLGDSGVGKSCLLMRFSDDRFTEKYLRTMGIDVKARSVELVSRVMMLQVWDTSGDKR 68
            :|||||:|::|||||||:|:|.|||:|.|...::.|:|||.|.|::||..:.:.||:|||:|.:|
Human     5 YDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQER 69

  Fly    69 FNSLMPSNYRSAHGILLVYDITSSKSFQNIDGWMKEIRRMCPDKVTVLLVGNKSDDPNHRQVSME 133
            |.::..:.||.|.||:||||||:.|||.||..|::.|.......|..:::|||.|..:.||||.|
Human    70 FRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKE 134

  Fly   134 QGFNYAHRGALGFEEVSAKSGMNVYDIFSSLAMDI 168
            :|...|....:.|.|.|||:.:||.:.|.:||.||
Human   135 RGEKLALDYGIKFMETSAKANINVENAFFTLARDI 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX2	NP_572627.1	RAB	8..171	CDD:197555	75/161 (47%)
RabX2	NP_572627.1	Rab	8..165	CDD:206640	71/156 (46%)
RAB8A	NP_005361.2	Rab8_Rab10_Rab13_like	6..172	CDD:206659	78/164 (48%)
RAB8A	NP_005361.2	Effector region. /evidence=ECO:0000250	37..45		3/7 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910