Protein Alignment RabX2 and RAB15

DIOPT Version :10

• Sequence 1: NP_572627.1
• Gene: RabX2 / 31971
• FlyBaseID: FBgn0030200
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: NP_001295083.1
• Gene: RAB15 / 376267
• HGNCID: 20150
• Length: 212
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 74/200 - (37%)
• Similarity: 121/200 - (60%)
• Gaps: 10/200 - (5%)

  Fly     4 FDYLFKVLVLGDSGVGKSCLLMRFSDDRFTEKYLRTMGIDVKARSVELVSRVMMLQVWDTSGDKR 68
            :|.||::|::|||||||:|||.||:|:.|...::.|:|:|.|.:::|:....:.:|:|||:|.:|
Human     5 YDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQIWDTAGQER 69

  Fly    69 FNSLMPSNYRSAHGILLVYDITSSKSFQNIDGWMKEIRRMCPDKVTVLLVGNKSDDPNHRQVSME 133
            :.::....||.|.||.|||||:|.:|:|:|..|:.::....|:.|..:|:|||:|:...|||..|
Human    70 YQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEYAPEGVQKILIGNKADEEQKRQVGRE 134

  Fly   134 QGFNYAHRGALGFEEVSAKSGMNVYDIFSSLAMDIY--HRYVLH-------NPISPMPSEQEEED 189
            ||...|....:.|.|.||.:.:|:.:.|:.|...:.  ||..|.       |.:: :...:|||.
Human   135 QGQQLAKEYGMDFYETSACTNLNIKESFTRLTELVLQAHRKELEGLRMRASNELA-LAELEEEEG 198

  Fly   190 AAESP 194
            ..|.|
Human   199 KPEGP 203

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RabX2	NP_572627.1	Rab	8..165	CDD:206640	62/156 (40%)
RAB15	NP_001295083.1	Rab15	9..172	CDD:206698	63/162 (39%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		3/13 (23%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		5/16 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	193..212		4/10 (40%)