DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX2 and rab-10

DIOPT Version :9

Sequence 1:	NP_572627.1	Gene:	RabX2 / 31971	FlyBaseID:	FBgn0030200	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_491857.1	Gene:	rab-10 / 266836	WormBaseID:	WBGene00004273	Length:	201	Species:	Caenorhabditis elegans

Alignment Length:	185	Identity:	78/185 - (42%)
Similarity:	116/185 - (62%)	Gaps:	9/185 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FDYLFKVLVLGDSGVGKSCLLMRFSDDRFTEKYLRTMGIDVKARSVELVSRVMMLQVWDTSGDKR 68
            :|.|||:|::|||||||:|:|.|||||.|...::.|:|||.|.:::||..:.:.||:|||:|.:|
Worm     6 YDMLFKLLLIGDSGVGKTCILYRFSDDAFNTTFISTIGIDFKIKTIELKGKKIKLQIWDTAGQER 70

  Fly    69 FNSLMPSNYRSAHGILLVYDITSSKSFQNIDGWMKEIRRMCPDKVTVLLVGNKSDDPNHRQVSME 133
            |:::..|.||.|.||:||||||::|||.||..|::.|.....:.|..:::|||.|..:.|.||.|
Worm    71 FHTITTSYYRGAMGIMLVYDITNAKSFDNIAKWLRNIDEHASEDVVKMILGNKCDMSDRRVVSRE 135

  Fly   134 QGFNYAHRGALGFEEVSAKSGMNVYDIFSSLAMDIYHRYVLHNPISPMPSEQEEE 188
            :|...|....:.|.|.|||..::|...|..||..|         ::.||...:|:
Worm   136 RGEKIAQDHGISFHETSAKLNVHVDTAFYDLAEAI---------LAKMPDSTDEQ 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX2	NP_572627.1	RAB	8..171	CDD:197555	73/162 (45%)
RabX2	NP_572627.1	Rab	8..165	CDD:206640	70/156 (45%)
rab-10	NP_491857.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	75/174 (43%)
rab-10	NP_491857.1	RAB	10..173	CDD:197555	73/171 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164606
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47980
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940