DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RabX2 and Rab12

DIOPT Version :9

Sequence 1:	NP_572627.1	Gene:	RabX2 / 31971	FlyBaseID:	FBgn0030200	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_037149.1	Gene:	Rab12 / 25530	RGDID:	3527	Length:	243	Species:	Rattus norvegicus

Alignment Length:	192	Identity:	76/192 - (39%)
Similarity:	115/192 - (59%)	Gaps:	5/192 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DYLFKVLVLGDSGVGKSCLLMRFSDDRFTEKYLRTMGIDVKARSVELVSRVMMLQVWDTSGDKRF 69
            |:..:|:::|..||||:.|:.||:||.|.|....|:|:|.|.::|||..:.:.||:|||:|.:||
  Rat    39 DFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQERF 103

  Fly    70 NSLMPSNYRSAHGILLVYDITSSKSFQNIDGWMKEIRRMCPDKVTVLLVGNKSDDPNHRQVSMEQ 134
            ||:..:.||||.||:||||||..::|.::..|||.|.:...:...:||||||.|....|::|.:|
  Rat   104 NSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCETDREISRQQ 168

  Fly   135 GFNYAHR-GALGFEEVSAKSGMNVYDIFSSLAMDIYHRYVLHNPISPMPSEQEEEDAAESPD 195
            |..:|.: ..:.|.|.|||...||.:||..|..||..:.    |:..:.||......:..|:
  Rat   169 GEKFAQQITGMRFCEASAKDNFNVDEIFLKLVDDILKKM----PLDVLRSELSNSILSLQPE 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RabX2	NP_572627.1	RAB	8..171	CDD:197555	71/163 (44%)
RabX2	NP_572627.1	Rab	8..165	CDD:206640	68/157 (43%)
Rab12	NP_037149.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..36
		Rab12	42..243	CDD:206699	75/189 (40%)
		Effector region. /evidence=ECO:0000250	70..78		2/7 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1149105at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010