Protein Alignment CG32683 and ARRB2

DIOPT Version :9

• Sequence 1: NP_001285084.1
• Gene: CG32683 / 31970
• FlyBaseID: FBgn0052683
• Length: 804
• Species: Drosophila melanogaster
• Sequence 2: XP_011522160.1
• Gene: ARRB2 / 409
• HGNCID: 712
• Length: 440
• Species: Homo sapiens
• Alignment Length: 534
• Identity: 133/534 - (24%)
• Similarity: 207/534 - (38%)
• Gaps: 197/534 - (36%)

  Fly   101 TQRVYKKTSPNCVLTLYLPTREITLTGNNPSVLRGIVYVDPKAIQGYRVYAQLTLTFRYGREDEE 165
            |:||:||:||||.||:||..|:.....:....:.|:|.|||..::..:|:..||..|||||||.:
Human    37 TRRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRYGREDLD 101

  Fly   166 VMGLRFCNEAIMSLHQIWPRLEEPTPESLSPLQEALMKRLGDGAHPFTLSLSSYAPPSVQLVPAK 230
            |:||.|..:..::.:|.:|.:..| |...:.||:.|:::||..||||..::....|.||.|.|..
Human   102 VLGLSFRKDLFIATYQAFPPVPNP-PRPPTRLQDRLLRKLGQHAHPFFFTIPQNLPCSVTLQPGP 165

  Fly   231 RYYGAPIGTSYDVRCFIADKTDEKFHRRASVKMGVRVIYRTDVFHQHLAPEQYAAFAGRQNIAQS 295
            ...|...|..:::|.|.|...:||.|:|.||::.:|.:             |:|
Human   166 EDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKV-------------QFA----------- 206

  Fly   296 PPASATPPSCGEGGEQHTTHTQQQSQSQPSSGSKHKSKSERGDSFPKLRLSPKSFRFSGRFGRSK 360
                                                                             
Human   207 ----------------------------------------------------------------- 206

  Fly   361 SEIEKCPNDPFHSYSKSFQEHCDSMLPPHTGAGVTGGIGGVSVGPCGGPQGSVD--KPFLLHDGR 423
                  |..|                                     |||.|.:  :.||:.|..
Human   207 ------PEKP-------------------------------------GPQPSAETTRHFLMSDRS 228

  Fly   424 VGLRASLDKGWYTHGEDVQVTVNIRNDSRKTVRKVRVCAIQHVDVCMFNNGKFKNVVADSDNVTP 488
            :.|.|||||..|.|||.:.|.|::.|:|.|||:|::|...|:.|:|:|:..::|..||..:.
Human   229 LHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQLEQ--- 290

  Fly   489 PVDRTVAAGASLNTTVTLRP--QRGPTKNWIALEDTLQRSTEPEEITGAIAASAIRSPHFVMQNA 551
              |..|:..::.....|:.|  .....|..:||:..|:     .|.|...:::.::.
Human   291 --DDQVSPSSTFCKVYTITPLLSDNREKRGLALDGKLK-----HEDTNLASSTIVKE-------- 340

  Fly   552 QLLGGCGHPLGSPALVTPHPHLWQPGSQGQGQPGNPNSGGGNEERNVFAIYVSYYVKVKLTLSGM 616
                                                   |.|:|  |..|.|||.|||||.:| .
Human   341 ---------------------------------------GANKE--VLGILVSYRVKVKLVVS-R 363

  Fly   617 GGELSLKLPFVLVH 630
            ||::|::|||||:|
Human   364 GGDVSVELPFVLMH 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32683	NP_001285084.1	Arrestin_N	135..268	CDD:304627	49/132 (37%)
		Arrestin_C	421..632	CDD:214976	60/212 (28%)
ARRB2	XP_011522160.1	Arrestin_N	50..206	CDD:278754	55/169 (33%)
		Arrestin_C	225..380	CDD:214976	60/213 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3865
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.802101	Normalized mean entropy	S2648
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D783081at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11792
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.870