DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32683 and Sag

DIOPT Version :9

Sequence 1:	NP_001285084.1	Gene:	CG32683 / 31970	FlyBaseID:	FBgn0052683	Length:	804	Species:	Drosophila melanogaster
Sequence 2:	NP_037155.2	Gene:	Sag / 25539	RGDID:	3619	Length:	403	Species:	Rattus norvegicus

Alignment Length:	545	Identity:	129/545 - (23%)
Similarity:	201/545 - (36%)	Gaps:	217/545 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 VYKKTSPNCVLTLYLPTREITLTGNNPSVLRGIVYVDPKAIQGYRVYAQLTLTFRYGREDEEVMG 168
            ::||.|.:..:|:||..|:.....:....:.|:|.|||:.::|.:||..||..||||:||.:|:|
  Rat    13 IFKKVSRDKSVTIYLGKRDYIDHVSQVEPVDGVVLVDPELVKGKKVYVTLTCAFRYGQEDIDVIG 77

  Fly   169 LRFCNEAIMSLHQIWP---RLEEPTPESLSPLQEALMKRLGDGAHPFTLSLSSYAPPSVQLVPAK 230
            |.|..:...|..|::|   .:..||     .||.:|:|:|||..:||.|:...|.|.||.|.||.
  Rat    78 LTFRRDLYFSRVQVYPPVGAMSAPT-----QLQLSLLKKLGDNTYPFLLTFPDYLPCSVMLQPAP 137

  Fly   231 RYYGAPIGTSYDVRCFIADKTD---EKFHRRASVKMGVRVIYRTDVFHQHLAPEQYAAFAGRQNI 292
            :..|...|..::|:.|..|.||   :|..:::||::.:|.:       ||..||.
  Rat   138 QDVGKSCGVDFEVKAFATDITDAEEDKIPKKSSVRLLIRKV-------QHAPPEM---------- 185

  Fly   293 AQSPPASATPPSCGEGGEQHTTHTQQQSQSQPSSGSKHKSKSERGDSFPKLRLSPKSFRFSGRFG 357
                    .|..|.|.                                        |::|
  Rat   186 --------GPQPCAEA----------------------------------------SWQF----- 197

  Fly   358 RSKSEIEKCPNDPFHSYSKSFQEHCDSMLPPHTGAGVTGGIGGVSVGPCGGPQGSVDKPFLLHDG 422
                         |.|                                        |||  ||
  Rat   198 -------------FMS----------------------------------------DKP--LH-- 205

  Fly   423 RVGLRASLDKGWYTHGEDVQVTVNIRNDSRKTVRKVRVCAIQHVDVCMFNNGKFKNVVADSDNVT 487
               |..||.|..|.|||.:.|||.:.|::.|.|:|::|...|..:|.::::..:...||..:
  Rat   206 ---LSVSLSKEIYFHGEPIPVTVTVTNNTEKVVKKIKVSVEQIANVVLYSSDYYVKPVASEE--- 264

  Fly   488 PPVDRTVAAGASLNTTVTL-------RPQRGPTKNWIALEDTLQRSTEPEEITGAIAASAIRSPH 545
              ....|...::|..|:.|       |.:||     |||:..::     .|.|...:::.|:.
  Rat   265 --TQEKVQPNSTLTKTLVLVPLLANNRERRG-----IALDGKIK-----HEDTNLASSTIIKE-- 315

  Fly   546 FVMQNAQLLGGCGHPLGSPALVTPHPHLWQPGSQGQGQPGNPNSGGGNEERNVFAIYVSYYVKVK 610
                                                           ..:|.|..|.|||::|||
  Rat   316 -----------------------------------------------GIDRTVMGILVSYHIKVK 333

  Fly   611 LTLSGMGGEL-----SLKLPFVLVH 630
            ||:||..|||     :.::||.|:|
  Rat   334 LTVSGFLGELTSSEVATEVPFRLMH 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32683	NP_001285084.1	Arrestin_N	135..268	CDD:304627	53/138 (38%)
CG32683	NP_001285084.1	Arrestin_C	421..632	CDD:214976	53/222 (24%)
Sag	NP_037155.2	Arrestin_N	23..181	CDD:419887	58/169 (34%)
		Arrestin_C	200..361	CDD:214976	59/270 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	381..403
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D783081at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11792
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020