DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32683 and Arrb2

DIOPT Version :9

Sequence 1:NP_001285084.1 Gene:CG32683 / 31970 FlyBaseID:FBgn0052683 Length:804 Species:Drosophila melanogaster
Sequence 2:NP_001258287.1 Gene:Arrb2 / 216869 MGIID:99474 Length:421 Species:Mus musculus


Alignment Length:536 Identity:138/536 - (25%)
Similarity:208/536 - (38%) Gaps:199/536 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   100 GTQRVYKKTSPNCVLTLYLPTREITLTGNNPSVLRGIVYVDPKAIQGYRVYAQLTLTFRYGREDE 164
            || ||:||:||||.||:||..|:.....:....:.|:|.|||..::..:|:..||..|||||||.
Mouse     6 GT-RVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRYGREDL 69

  Fly   165 EVMGLRFCNEAIMSLHQIWPRLEEPTPESLSPLQEALMKRLGDGAHPFTLSLSSYAPPSVQLVPA 229
            :|:||.|..:..::.:|.:|.:..| |...:.||:.|:|:||..||||..::....|.||.|.|.
Mouse    70 DVLGLSFRKDLFIATYQAFPPMPNP-PRPPTRLQDRLLKKLGQHAHPFFFTIPQNLPCSVTLQPG 133

  Fly   230 KRYYGAPIGTSYDVRCFIADKTDEKFHRRASVKMGVRVIYRTDVFHQHLAPEQYAAFAGRQNIAQ 294
            ....|...|..:::|.|.|...:||.|:|.||::.:|.:        ..|||             
Mouse   134 PEDTGKACGVDFEIRAFCAKSIEEKSHKRNSVRLIIRKV--------QFAPE------------- 177

  Fly   295 SPPASATPPSCGEGGEQHTTHTQQQSQSQPSSGSKHKSKSERGDSFPKLRLSPKSFRFSGRFGRS 359
                  ||                                                         
Mouse   178 ------TP--------------------------------------------------------- 179

  Fly   360 KSEIEKCPNDPFHSYSKSFQEHCDSMLPPHTGAGVTGGIGGVSVGPCGGPQGSVD--KPFLLHDG 422
                                                            |||.|.:  :.||:.|.
Mouse   180 ------------------------------------------------GPQPSAETTRHFLMSDR 196

  Fly   423 R-VGLRASLDKGWYTHGEDVQVTVNIRNDSRKTVRKVRVCAIQHVDVCMFNNGKFKNVVADSDNV 486
            | :.|.|||||..|.|||.:.|.|::.|:|.|||:|:||...|:.|:|:|:..::|..||..:. 
Mouse   197 RSLHLEASLDKELYYHGEPLNVNVHVTNNSAKTVKKIRVSVRQYADICLFSTAQYKCPVAQLEQ- 260

  Fly   487 TPPVDRTVAAGASLNTTVTLRP--QRGPTKNWIALEDTLQRSTEPEEITGAIAASAIRSPHFVMQ 549
                |..|:..::.....|:.|  .....|..:||:..|:     .|.|...:::.::.      
Mouse   261 ----DDQVSPSSTFCKVYTITPLLSDNREKRGLALDGQLK-----HEDTNLASSTIVKE------ 310

  Fly   550 NAQLLGGCGHPLGSPALVTPHPHLWQPGSQGQGQPGNPNSGGGNEERNVFAIYVSYYVKVKLTLS 614
                                                     |.|:|  |..|.|||.|||||.:|
Mouse   311 -----------------------------------------GANKE--VLGILVSYRVKVKLVVS 332

  Fly   615 GMGGELSLKLPFVLVH 630
             .||::|::|||||:|
Mouse   333 -RGGDVSVELPFVLMH 347

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG32683NP_001285084.1 Arrestin_N 135..268 CDD:304627 50/132 (38%)
Arrestin_C 421..632 CDD:214976 62/213 (29%)
Arrb2NP_001258287.1 Arrestin_N 19..175 CDD:334019 55/164 (34%)
Arrestin_C 199..350 CDD:214976 60/209 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3865
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0.802101 Normalized mean entropy S2648
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D783081at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11792
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
54.870

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