Protein Alignment CG32683 and Sag

DIOPT Version :10

• Sequence 1: NP_727419.1
• Gene: CG32683 / 31970
• FlyBaseID: FBgn0052683
• Length: 804
• Species: Drosophila melanogaster
• Sequence 2: NP_033144.1
• Gene: Sag / 20215
• MGIID: 98227
• Length: 403
• Species: Mus musculus
• Alignment Length: 544
• Identity: 124/544 - (22%)
• Similarity: 198/544 - (36%)
• Gaps: 215/544 - (39%)

  Fly   104 VYKKTSPNCVLTLYLPTREITLTGNNPSVLRGIVYVDPKAIQGYRVYAQLTLTFRYGREDEEVMG 168
            ::||.|.:..:|:||..|:.....:....:.|:|.|||:.::|.:||..||..||||:||.:|||
Mouse    13 IFKKVSRDKSVTIYLGKRDYVDHVSQVEPVDGVVLVDPELVKGKKVYVTLTCAFRYGQEDIDVMG 77

  Fly   169 LRFCNEAIMSLHQIWPRLEEPTPESLSPLQEALMKRLGDGAHPFTLSLSSYAPPSVQLVPAKRYY 233
            |.|..:...|..|::|.:  .....|:.|||:|:|:|||..:||.|:...|.|.||.|.||.:..
Mouse    78 LTFRRDLYFSRVQVYPPV--GAMSVLTQLQESLLKKLGDNTYPFLLTFPDYLPCSVMLQPAPQDV 140

  Fly   234 GAPIGTSYDVRCFIADKTD---EKFHRRASVKMGVRVIYRTDVFHQHLAPEQYAAFAGRQNIAQS 295
            |...|..::|:.|.:|.||   :|..:::||::.:|.:       ||..||.
Mouse   141 GKSCGVDFEVKAFASDITDPEEDKIPKKSSVRLLIRKV-------QHAPPEM------------- 185

  Fly   296 PPASATPPSCGEGGEQHTTHTQQQSQSQPSSGSKHKSKSERGDSFPKLRLSPKSFRFSGRFGRSK 360
                                                                             
Mouse   186 ----------------------------------------------------------------- 185

  Fly   361 SEIEKCPNDPFHSYSKSFQEHCDSMLPPHTGAGVTGGIGGVSVGPCGGPQGSVDK--PFLLHDGR 423
                                                           |||.|.:.  .|.:.|..
Mouse   186 -----------------------------------------------GPQPSAEASWQFFMSDKP 203

  Fly   424 VGLRASLDKGWYTHGEDVQVTVNIRNDSRKTVRKVRVCAIQHVDVCMFNNGKFKNVVADSDNVTP 488
            :.|..||.|..|.|||.:.|||.:.|::.|.|:|::|...|..:|.::::..:...||..:
Mouse   204 LNLSVSLSKEIYFHGEPIPVTVTVTNNTDKVVKKIKVSVEQIANVVLYSSDYYVKPVASEE---- 264

  Fly   489 PVDRTVAAGASLNTTVTL-------RPQRGPTKNWIALEDTLQRSTEPEEITGAIAASAIRSPHF 546
             ....|...::|..|:.|       |.:||     |||:..::     .|.|...:::.|:.
Mouse   265 -TQEKVQPNSTLTKTLVLVPLLANNRERRG-----IALDGKIK-----HEDTNLASSTIIKE--- 315

  Fly   547 VMQNAQLLGGCGHPLGSPALVTPHPHLWQPGSQGQGQPGNPNSGGGNEERNVFAIYVSYYVKVKL 611
                                                          ..:|.|..|.|||::||||
Mouse   316 ----------------------------------------------GIDRTVMGILVSYHIKVKL 334

  Fly   612 TLSGMGGEL-----SLKLPFVLVH 630
            |:||..|||     :.::||.|:|
Mouse   335 TVSGFLGELTSSEVATEVPFRLMH 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32683	NP_727419.1	Arrestin_N	135..268	CDD:451447	54/135 (40%)
		Arrestin_C	421..632	CDD:214976	54/222 (24%)
Sag	NP_033144.1	Interaction with RHO. /evidence=ECO:0000269|PubMed:28753425	11..19		2/5 (40%)
		Arrestin_N	23..181	CDD:451447	59/166 (36%)
		Arrestin_C	200..361	CDD:214976	54/223 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	381..403