Protein Alignment Psf3 and GINS3

DIOPT Version :10

• Sequence 1: NP_572624.1
• Gene: Psf3 / 31967
• FlyBaseID: FBgn0030196
• Length: 212
• Species: Drosophila melanogaster
• Sequence 2: NP_001119601.1
• Gene: GINS3 / 64785
• HGNCID: 25851
• Length: 255
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 65/241 - (26%)
• Similarity: 107/241 - (44%)
• Gaps: 54/241 - (22%)

  Fly     9 NYYSIEDIFVTQEKVECRVNTKLQRMG--FLD--SGAESDDLEP--------------------- 48
            |:.|::||.::.||:..|..|.:.|:|  ||:  :|||:|:..|
Human    18 NFLSLDDILMSHEKLPVRTETAMPRLGAFFLERSAGAETDNAVPQGFALLPRLECSGVIWLTAAL 82

  Fly    49 -------------------GRTVNLPLWYIKELKVN-NAYFTVAVPDIYRNVHKAVCEAETTHIE 93
                               |..:.||||..|.|..| ....:|.:|.||:...:.|..|:...::
Human    83 TSQAPEILPPQPPMWLVLQGSKLELPLWLAKGLFDNKRRILSVELPKIYQEGWRTVFSADPNVVD 147

  Fly    94 LGRLHPYFYEFGRYLTPYD--RNHVIGRIIFETLRQRVRHLLDISKS----DGQAAKAEHRLDNI 152
            |.::.|:||.||..|..:|  .|..|.:.:.:|...|.|.::|.|::    |..|..|  |||.:
Human   148 LHKMGPHFYGFGSQLLHFDSPENADISQSLLQTFIGRFRRIMDSSQNAYNEDTSALVA--RLDEM 210

  Fly   153 EAKLHEAGVRTNSQYIEWLQMTGNKIRTSELVEEHQKKRRRADRSD 198
            |..|.:.|.:..:.:..|.:...::|..|.||:.: |||:..|..|
Human   211 ERGLFQTGQKGLNDFQCWEKGQASQITASNLVQNY-KKRKFTDMED 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Psf3	NP_572624.1	GINS_B_Psf3	10..74	CDD:412029	25/108 (23%)
		GINS_A_psf3	68..173	CDD:212551	31/110 (28%)
GINS3	NP_001119601.1	GINS_B_Psf3	19..128	CDD:412029	25/108 (23%)
		GINS_A_psf3	122..231	CDD:212551	31/110 (28%)