Protein Alignment l(1)G0289 and PLXDC2

DIOPT Version :10

• Sequence 1: NP_001401057.1
• Gene: l(1)G0289 / 31964
• FlyBaseID: FBgn0028331
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: XP_011518052.1
• Gene: PLXDC2 / 84898
• HGNCID: 21013
• Length: 564
• Species: Homo sapiens
• Alignment Length: 524
• Identity: 173/524 - (33%)
• Similarity: 251/524 - (47%)
• Gaps: 91/524 - (17%)

  Fly   132 RKTYDVAPAVDSNTTSQMAPATKKPTLLGQ-SGNPKKVASSVVAATMTDPSPAVIDVDVSKVVDV 195
            ::..|...|||:|..|           :|| |..|:         :.||   .::|
Human    66 KRNLDFLKAVDTNRAS-----------VGQDSPEPR---------SFTD---LLLD--------- 98

  Fly   196 PEEEIEAAVKNASLKESVDFHEYYNSVLYENKDEVA-SLWTELKATPENI-----MLSSSHRRAM 254
                 :....|..::|..| |.||.|.:|...|..: .||..:....::.     :||::||:|.
Human    99 -----DGQDNNTQIEEDTD-HNYYISRIYGPSDSASRDLWVNIDQMEKDKVKIHGILSNTHRQAA 157

  Fly   255 TVELKFDFPFYGHFVRNITVATGGFLYTGEYVHSWLAATQYIAPLMANFDTSMSNDSFVRLHDNG 319
            .|.|.|||||||||:|.||||||||:||||.||..|.|||||||||||||.|:|.:|.||..|||
Human   158 RVNLSFDFPFYGHFLREITVATGGFIYTGEVVHRMLTATQYIAPLMANFDPSVSRNSTVRYFDNG 222

  Fly   320 TAFTAVWENVTLQDKPDFGKFTFSVTLYQSGDIVFAYMLVPTNINSIQDKEHPVKVGLSDAYII- 383
            ||....|::|.|||..:.|.|||..||...|.|:|.|..:|..:..|....||||||||||:::
Human   223 TALVVQWDHVHLQDNYNLGSFTFQATLLMDGRIIFGYKEIPVLVTQISSTNHPVKVGLSDAFVVV 287

  Fly   384 --DKQLFFARRKTIYEYHRVTFQQHEITNNTIIKLAAQPTCLGYNDCNSCINHNTTFTCLWCSVL 446
              .:|:...||:||||||||..|..:|||.:.:::...||||.:|.|..|::....|.|.|||.|
Human   288 HRIQQIPNVRRRTIYEYHRVELQMSKITNISAVEMTPLPTCLQFNRCGPCVSSQIGFNCSWCSKL 352

  Fly   447 NRCSTGTDRKKHEWLQMGCEATAIHTSSLCPALGDKGNNAAGQGKNGSANSGASANGATNTSTSS 511
            .|||:|.||.:.:|:..||...:  ...:|                    ........::.:|::
Human   353 QRCSSGFDRHRQDWVDSGCPEES--KEKMC--------------------ENTEPVETSSRTTTT 395

  Fly   512 SGSSTPVTEPSVMSTRAPHATAYIKPGVDHSSD----IHADGKVGNAELSKAEADNK----NVGV 568
            .|::|  |:..|::|.....|:.....:....|    :|.  |...|....:.|:.|    :.|:
Human   396 VGATT--TQFRVLTTTRRAVTSQFPTSLPTEDDTKIALHL--KDNGASTDDSAAEKKGGTLHAGL 456

  Fly   569 AFGFMVPICLVFAVTLWLFYAYRNPHTKSGQLLIQ------SKQFRPSQWSWRR--GEARYTAA- 624
            ..|.::.:.:|....|...|.|.:|.:.:....|:      .|......|..|.  |:.|:.|.
Human   457 IIGILILVLIVATAILVTVYMYHHPTSAASIFFIELWKSEVLKSGYGQGWFLREASGDNRFLAIF 521

  Fly   625 TIHM 628
            :.||
Human   522 SFHM 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(1)G0289	NP_001401057.1	PSI	421..477	CDD:396154	21/55 (38%)
PLXDC2	XP_011518052.1	NIDO	191..>282	CDD:470642	48/90 (53%)
		PSI	327..372	CDD:396154	20/44 (45%)