DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15306 and VCX3A

DIOPT Version :9

Sequence 1:	NP_001259403.1	Gene:	CG15306 / 31961	FlyBaseID:	FBgn0030191	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_057463.2	Gene:	VCX3A / 51481	HGNCID:	18159	Length:	186	Species:	Homo sapiens

Alignment Length:	152	Identity:	39/152 - (25%)
Similarity:	74/152 - (48%)	Gaps:	21/152 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 KVKTTAI-----------RGK--VATCQATINSSLC-TGKA---NQDEDSQHTDKKD---EDSRD 203
            |.|||.:           |||  .||..|.:.:... :|.|   ..|:.||...:.:   |:...
Human    32 KKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVS 96

  Fly   204 QGSQYEDSPGMDSQYKDCRDQDSQYEDSHGKDSQYKDCRDQGSQYEDSHGMDSQYEDSRDQDSQY 268
            :|:|: |....:|:.::...|:|:.|:...::||.::...|.|:.|:....:||.|:...|:|:.
Human    97 EGTQH-DPLSQESELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEV 160

  Fly   269 EDSPGMDSQYKDSRDQDSQYED 290
            |:....:||.::...|:|:.|:
Human   161 EEPLSQESQVEEPLSQESEMEE 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15306	NP_001259403.1	CH	20..103	CDD:278723
VCX3A	NP_057463.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..186		39/152 (26%)
		VCX_VCY	1..141	CDD:291884	27/109 (25%)
		8 X 10 AA tandem repeats of L-S-Q-E-S-[EQ]-V-E-E-P	104..183		20/79 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910