DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15306 and Mapre1

DIOPT Version :9

Sequence 1:	NP_001259403.1	Gene:	CG15306 / 31961	FlyBaseID:	FBgn0030191	Length:	357	Species:	Drosophila melanogaster
Sequence 2:	NP_612518.2	Gene:	Mapre1 / 114764	RGDID:	621781	Length:	268	Species:	Rattus norvegicus

Alignment Length:	141	Identity:	62/141 - (43%)
Similarity:	87/141 - (61%)	Gaps:	6/141 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 HNVTVTHNSLVQWSRGDILDWFNETLQCNLINIEQLCTGAAYCNLMHMLYPKLINLKRVKFFSNQ 71
            ::.:||.::|   ||.|:|.|.||:||.||..|||||:|||||..|.||:|..|.||:|||.:..
  Rat     6 YSTSVTSDNL---SRHDMLAWINESLQLNLTKIEQLCSGAAYCQFMDMLFPGSIALKKVKFQAKL 67

  Fly    72 EYEYVNNFKELQKAFNKVNVSLPAEVNDLIKGHRVENFKFAVWFRHFFNVNHTKDKCAGYDALVA 136
            |:||:.|||.||..|.::.|.....|:.|:||...:||:|..||:.||:.|:...:   ||.:.|
  Rat    68 EHEYIQNFKILQAGFKRMGVDKIIPVDKLVKGKFQDNFEFVQWFKKFFDANYDGKE---YDPVAA 129

  Fly   137 RDHQNIGIGSS 147
            |..|...:..|
  Rat   130 RQGQETAVAPS 140

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15306	NP_001259403.1	CH	20..103	CDD:278723	43/82 (52%)
Mapre1	NP_612518.2	BIM1	16..257	CDD:227542	59/128 (46%)
		Interaction with MTUS2/TIP150. /evidence=ECO:0000250	124..268		6/17 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	146..191
		DCTN1-binding. /evidence=ECO:0000250	208..268
		APC-binding. /evidence=ECO:0000250	220..242
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352827
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5217
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1237523at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10623
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.810