Protein Alignment CG15306 and MAPRE2

DIOPT Version :10

• Sequence 1: NP_572618.1
• Gene: CG15306 / 31961
• FlyBaseID: FBgn0030191
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_055083.1
• Gene: MAPRE2 / 10982
• HGNCID: 6891
• Length: 327
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 84/301 - (27%)
• Similarity: 132/301 - (43%)
• Gaps: 50/301 - (16%)

  Fly     9 VTVTHNSLVQ--WSRGDILDWFNETLQCNLINIEQLCTGAAYCNLMHMLYPKLINLKRVKFFSNQ 71
            |.|...|:.|  .||.||:.|.|:.:..|...:||||:|||||..|.||:|..|:||:|||.:..
Human    46 VNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKL 110

  Fly    72 EYEYVNNFKELQKAFNKVNVSLPAEVNDLIKGHRVENFKFAVWFRHFFNVNHTKDKCAGYDALVA 136
            |:||::|||.||.:|.::||.....|..|:||...:|..|..||:.|::.|:...:   ||.:.|
Human   111 EHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKE---YDPVEA 172

  Fly   137 RDHQNIGIGSSKLTTKDR----FRLVKV-----KTTAIRGKVATCQATINSSLCTGKANQDEDSQ 192
            |.      |...:...|.    |.|.|.     ..||...|.:......::......|.:...|.
Human   173 RQ------GQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSSG 231

  Fly   193 HTDKKDEDSRDQGSQYEDS--------PGMDSQYKDCRDQDSQYEDSHGKDSQYK-DCRDQGSQY 248
            ...|.|:|...|..|..:.        .|::      :::|..:    ||..:.: .|::.|.:.
Human   232 SASKSDKDLETQVIQLNEQVHSLKLALEGVE------KERDFYF----GKLREIELLCQEHGQEN 286

  Fly   249 ED--SHGMDSQY---------EDSRDQDSQYEDSPGMDSQY 278
            :|  ...||..|         |:...::..:|..|....:|
Human   287 DDLVQRLMDILYASEEHEGHTEEPEAEEQAHEQQPPQQEEY 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15306	NP_572618.1	CH	18..124	CDD:425596	48/107 (45%)
		MSCRAMM_ClfA	<185..346	CDD:468110	21/114 (18%)
MAPRE2	NP_055083.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		BIM1	59..313	CDD:227542	77/272 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..240		14/74 (19%)
		DCTN1-binding	187..327		26/149 (17%)
		APC-binding	259..302		10/52 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..327		3/27 (11%)