DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gip and hyi

DIOPT Version :9

Sequence 1:	NP_511106.1	Gene:	Gip / 31960	FlyBaseID:	FBgn0011770	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_415041.1	Gene:	hyi / 946186	ECOCYCID:	G6277	Length:	258	Species:	Escherichia coli

Alignment Length:	258	Identity:	91/258 - (35%)
Similarity:	146/258 - (56%)	Gaps:	8/258 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LKFAANLNFLFTERATSIAERIRLAHQNGFRAVEIPYP-EGETSDVVSAVKETGVVVSLVNL-AF 65
            |:|:|||:.||.|  .....|...|.|.|||.||..:| :.:..::...:....:..:|.|| |.
E. coli     2 LRFSANLSMLFGE--YDFLARFEKAAQCGFRGVEFMFPYDYDIEELKHVLASNKLEHTLHNLPAG 64

  Fly    66 DKSDDQLRFGSTSVPGSEKLFRSQLDATIDFARQVNCGKIHLTAGLFKGGQESDYT-KTYTANLK 129
            |.:..:.  |...:||.|:.||..:.|.|.:||.:...||:...|....|..|:.. .|...||:
E. coli    65 DWAAGER--GIACIPGREEEFRDGVAAAIRYARALGNKKINCLVGKTPAGFSSEQIHATLVENLR 127

  Fly   130 IAADSLRASKMIGVIEPINKYAVPGYYMNSYSKAAGILADVAADNIQLLADLYHLQHLHGNVSKT 194
            .||:.|....::.:|||||.:.:||:::....:|..::.||...|:::..|:||:|.:.|.::.|
E. coli   128 YAANMLMKEDILLLIEPINHFDIPGFHLTGTRQALKLIDDVGCCNLKIQYDIYHMQRMEGELTNT 192

  Fly   195 LEEYKALIGHFQIAQVPHRHEPDVSGELDYGFVFKALQEFGYDGWIGCEYKPKTTTVEGLGWV 257
            :.::...|||.|||..|||.||. :||::|.::||.::...|:||:||||||:|||..||.|:
E. coli   193 MTQWADKIGHLQIADNPHRGEPG-TGEINYDYLFKVIENSDYNGWVGCEYKPQTTTEAGLRWM 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gip	NP_511106.1	OH-pyruv-isom	4..256	CDD:163190	89/254 (35%)
Gip	NP_511106.1	AP_endonuc_2	24..222	CDD:279585	63/200 (32%)
hyi	NP_415041.1	PRK09997	1..258	CDD:182188	91/258 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	93	1.000	Domainoid score	I391
eggNOG	1	0.900	-	-		E1_COG3622
Hieranoid	1	1.000	-	-
Inparanoid	1	1.050	160	1.000	Inparanoid score	I203
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005694
OrthoInspector	1	1.000	-	-		otm51332
orthoMCL	1	0.900	-	-		OOG6_106707
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4089
SwiftOrtho	0	0.000	Not matched by this tool.
	9	8.760