Protein Alignment alpha-Man-Ia and MNS1

DIOPT Version :10

• Sequence 1: NP_727408.2
• Gene: alpha-Man-Ia / 31957
• FlyBaseID: FBgn0259170
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_012665.3
• Gene: MNS1 / 853595
• SGDID: S000003892
• Length: 549
• Species: Saccharomyces cerevisiae
• Alignment Length: 518
• Identity: 175/518 - (33%)
• Similarity: 263/518 - (50%)
• Gaps: 79/518 - (15%)

  Fly   209 NPGGIQFERRAHVKQMMEHAWHNYKLYAWGKNELRPLSQRPHSASIFGSYDLGATIVDGLDTLYI 273
            :||.  .|.|..::.|...:|.:|..:.||.:...|:....|:.. .|:..||..|||.:|||.:
Yeast    32 SPGA--GEMRDRIESMFLESWRDYSKHGWGYDVYGPIEHTSHNMP-RGNQPLGWIIVDSVDTLML 93

  Fly   274 M---------GLEKEYREGRDWIERKFSLDNISAELSVFETNIRFVGGMLTLYAFT------GDP 323
            |         ..|.|.:....||......| |.||::||||.||.:||:|:.|..:      ...
Yeast    94 MYNSSTLYKSEFEAEIQRSEHWINDVLDFD-IDAEVNVFETTIRMLGGLLSAYHLSDVLEVGNKT 157

  Fly   324 LYKEKAQHVADKLLPAF-QTPTGIPYALVNTKTGVA-KNYGWASGGSSILSEFGTLHLEFAYLSD 386
            :|..||..:.|:|..|| .|.|||||:.:|..:|.| ||:  |.||:|..:||.||.:||.||:.
Yeast   158 VYLNKAIDLGDRLALAFLSTQTGIPYSSINLHSGQAVKNH--ADGGASSTAEFTTLQMEFKYLAY 220

  Fly   387 ITGNPLYRERVQTIRQVLKE----IEKPKGLYPNFLNPKTGKWGQLHMSLGALGDSYYEYLLKAW 447
            :|||..|.|.|:.:.:.|.:    :....||.|.:..|.|||:|...:..|:.|||:||||||.:
Yeast   221 LTGNRTYWELVERVYEPLYKNNDLLNTYDGLVPIYTFPDTGKFGASTIRFGSRGDSFYEYLLKQY 285

  Fly   448 LQSGQT---DEEAREMFDEAMLAILDKMVRTSPGGLTYVSDLK---FDRLEHKMDHLACFSGGLF 506
            |.:.:|   |...:.|  |.|...|  :.::.|..|.|:.:.:   ..:|..|||||.||.|||.
Yeast   286 LLTHETLYYDLYRKSM--EGMKKHL--LAQSKPSSLWYIGEREQGLHGQLSPKMDHLVCFMGGLL 346

  Fly   507 ALGAA------------------TRQNDYTDKYMEVGKGITNTCHESYIRAPTQLGPEAFRFSE- 552
            |.|:.                  .|::|:     ::.||||:||::.|.::.:.|.||...|::
Yeast   347 ASGSTEGLSIHEARRRPFFSLSLERKSDW-----DLAKGITDTCYQMYKQSSSGLAPEIVVFNDG 406

  Fly   553 ----------AVEARALRSQEKYYILRPETFESYFVLWRLTHDQKYRDWGWE-AVLALEKHCRTA 606
                      :|....::..:::.:.||||.||...::.|:||.|||:||.| |....|..|...
Yeast   407 NIKQDGWWRSSVGDFFVKPLDRHNLQRPETVESIMFMYHLSHDHKYREWGAEIATSFFENTCVDC 471

  Fly   607 HG-----YCGLRNVYQQEPQKDDVQQSFFLAETLKYLYLLFSDDSVLPLDEWVFNTEAHPLPI 664
            :.     :..|.:......:|.:..:||:|||||||||:||.|:  ..|.:.||||||||.|:
Yeast   472 NDPKLRRFTSLSDCITLPTKKSNNMESFWLAETLKYLYILFLDE--FDLTKVVFNTEAHPFPV 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ia	NP_727408.2	LanC_like	216..664	CDD:471159	172/509 (34%)
MNS1	NP_012665.3	Glyco_hydro_47	45..532	CDD:460241	170/501 (34%)