Protein Alignment alpha-Man-Ia and man1b1a

DIOPT Version :10

• Sequence 1: NP_727408.2
• Gene: alpha-Man-Ia / 31957
• FlyBaseID: FBgn0259170
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_005161175.1
• Gene: man1b1a / 562592
• ZFINID: ZDB-GENE-091116-34
• Length: 682
• Species: Danio rerio
• Alignment Length: 629
• Identity: 222/629 - (35%)
• Similarity: 337/629 - (53%)
• Gaps: 60/629 - (9%)

  Fly    72 YSTLQQHHLSRSDLNYIQAATHPKNLQRQLQQQQQQQLQQQQPN---KIVIEIGLSN---DSGPS 130
            ||:|.:.....||          ::|:....:...:.|:...|.   |:...:|:.:   |..|.
Zfish    73 YSSLTEQWRGISD----------RSLKEDWDEVDNRGLRPIPPGLIPKLSAGVGVQDVQPDVMPE 127

  Fly   131 ---------SAPASSTLGSSSTGPRILQ-----AAEALMEGNVDSISLPAAAPLTAATTSSAKS- 180
                     ..|.:.....|..||..||     :...|.:|....|.........|.|..|.:.
Zfish   128 LQKPSIPLLPKPPAMRKPPSKRGPPALQKRMNVSDWQLKDGEEGLIKTDEDGAKEAKTVISWRGA 192

  Fly   181 -LENSQGSDTPHSHANTTNADITM----GIADHNPGGIQ-FERRAHVKQMMEHAWHNYKLYAWGK 239
             :|..||::.   .:.....|.|:    ..||...|.:: .:|...|::...|||..||.:|||.
Zfish   193 MIEAEQGTEL---QSTIQGKDATVVDAEEAADLKTGTLKPVDRVEAVQEAFRHAWKGYKAFAWGH 254

  Fly   240 NELRPLSQRPHSASIFGSYDLGATIVDGLDTLYIMGLEKEYREGRDWIERKFSLDNISAELSVFE 304
            :||:||| :.| ...||   ||.|::|.|||::|:||:.|:.|.|.|:|.:.|... :.::::||
Zfish   255 DELKPLS-KTH-GEWFG---LGLTLIDALDTMWILGLKDEFAEARKWVETELSFSK-NVDVNLFE 313

  Fly   305 TNIRFVGGMLTLYAFTGDPLYKEKAQHVADKLLPAFQTPTGIPYALVNTKTGVAKNYGWASGGSS 369
            :.||.:||:|:.|..:||.|:.:||:.:..:|:|||:||:.|||:.||...|.|....|.:  .|
Zfish   314 STIRILGGLLSTYHLSGDTLFLDKAKDIGFRLMPAFKTPSKIPYSDVNIGKGTAHPPRWTT--DS 376

  Fly   370 ILSEFGTLHLEFAYLSDITGNPLYRERVQTIRQVLKEIE-KPKGLYPNFLNPKTGKWGQL-HMSL 432
            .::|..::.|||..||.:|.:|.|:..|:.:.:.:..:| |..||.|.|:|..:||:.:. ..:|
Zfish   377 TVAEVTSIQLEFRELSRLTQDPQYQNAVEEVTKQVHRLEGKRDGLVPMFINTNSGKFTRRGAFTL 441

  Fly   433 GALGDSYYEYLLKAWLQSGQTDEEAREMFDEAMLAILDKMVR-TSPGGLTYVSDLKFDRLEHKMD 496
            ||..|||||||||.|||.|:.:.|..|.:.:|:..:...::: ||...||:|.:|...||..|||
Zfish   442 GARADSYYEYLLKQWLQGGKKETELLEDYIQAIEGVKKNLLKQTSTSKLTFVGELSNGRLNPKMD 506

  Fly   497 HLACFSGGLFALGAATRQNDYTDKYMEVGKGITNTCHESYIRAPTQLGPEAFRFS-EAVEARAL- 559
            ||.||..|..||||   .|.....:||:...:..|||:.|::..|.|.||...|: :....|.:
Zfish   507 HLVCFLPGTLALGA---HNGLPADHMELAIQLIETCHQMYVQMETGLSPEIAHFNLQNHNGRDID 568

  Fly   560 -RSQEKYYILRPETFESYFVLWRLTHDQKYRDWGWEAVLALEKHCRT-AHGYCGLRNVYQQ-EPQ 621
             :..:::.:|||||.||.|.::|.|.|.||||||||.:.:..||.|. :.||..:.||... .|.
Zfish   569 VKPADRHNLLRPETVESLFYMYRFTKDSKYRDWGWEILQSFNKHTRVPSGGYTSIGNVRDPLNPA 633

  Fly   622 KDDVQQSFFLAETLKYLYLLFSDDS-VLPLDEWVFNTEAHPLPI 664
            ..|..:||||:||||||:||||||: ::.||::|||||||||||
Zfish   634 PRDKMESFFLSETLKYLFLLFSDDTELISLDKYVFNTEAHPLPI 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ia	NP_727408.2	LanC_like	216..664	CDD:471159	188/456 (41%)
man1b1a	XP_005161175.1	Glyco_hydro_47	239..677	CDD:460241	186/448 (42%)