Protein Alignment alpha-Man-Ia and edem3

DIOPT Version :10

• Sequence 1: NP_727408.2
• Gene: alpha-Man-Ia / 31957
• FlyBaseID: FBgn0259170
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_005166989.2
• Gene: edem3 / 559811
• ZFINID: ZDB-GENE-070801-5
• Length: 888
• Species: Danio rerio
• Alignment Length: 511
• Identity: 156/511 - (30%)
• Similarity: 233/511 - (45%)
• Gaps: 95/511 - (18%)

  Fly   218 RAHVKQMMEHAWHNYKLYAWGKNELRPLSQR-------PHSASI---FGSYDLGATIVDGLDTLY 272
            |..|.:|.:||:.||..:|:..:||.||:.|       |....:   .|.:.|  |::|.||||.
Zfish    38 RIQVLEMFDHAYRNYMDHAYPADELMPLTCRGRVRGLEPSRGDVDDALGKFSL--TLIDTLDTLA 100

  Fly   273 IMGLEKEYREGRDWIERKFSLDNISAELSVFETNIRFVGGMLTLYAFTGDPLYKEKAQ------- 330
            ::....|:.|....:.:...||| ...:||||||||.:||:|..::..  .:.||..|
Zfish   101 LLNKTVEFEEAVRRVVKDVRLDN-DIVVSVFETNIRVLGGLLGGHSMA--VMLKENGQMVWYQNE 162

  Fly   331 --HVAD----KLLPAFQTPTGIPYALVN---------TKTGVAKNYGWASGGSSILSEFGTLHLE 380
              |:|.    :|||||.|.:|:||..||         |:||.......|..        ||:.||
Zfish   163 LLHMAKDLGLRLLPAFNTSSGLPYPRVNLRHGVHGPETRTGTETETCTACA--------GTIILE 219

  Fly   381 FAYLSDITGNPLYRERVQTIRQVL-KEIEKPKGLYPNFLNPKTGKWGQLHMSLGALGDSYYEYLL 444
            ||.||..||:|.:....:.....| ::.::...|....:|..:|:|.:....:||..|||||||:
Zfish   220 FAALSRFTGDPTFEAHARRALDFLWEKRQRNSNLVGTTINIHSGEWVRRDSGVGAGIDSYYEYLM 284

  Fly   445 KAWLQSGQTDEEAREMFDEAMLAILDKMVRTSPGGLTYVSDLKFDRLEHK--------MDHLACF 501
            ||::..|  |::....|:....:|: |.:...|        |..|...||        ||.|..|
Zfish   285 KAYILLG--DDQLLLRFNTHYASIM-KYISQPP--------LLLDVHIHKPLLPARTWMDSLLAF 338

  Fly   502 SGGLFALGAATRQNDYTDKYMEVGKGITNTCHESYIRAPTQLG--PEAFRFSEAVEARALRSQEK 564
            ..||..|....|....|              ||...:...:..  ||||    ..:.|...:|
Zfish   339 FPGLQVLKGDIRPAIET--------------HEMLYQVTKKHNFLPEAF----TTDFRVHWAQ-- 383

  Fly   565 YYILRPETFESYFVLWRLTHDQKYRDWGWEAVLALEKHCRTAHGYCGLRNVYQQEPQKDDVQQSF 629
             :.||||..||.:.|::.|.|..|.:.|...:..|.:..|...|:..:::|  :....:|...||
Zfish   384 -HPLRPEFAESTYFLYKATRDPYYLEVGRTVLENLNRFARVPCGFAAMKDV--RTGSHEDRMDSF 445

  Fly   630 FLAETLKYLYLLFSDDSVLP--LDEWVFNTEAHPLPIKGANAYYRQAPVTLPVSNA 683
            ||||..|||:|||:::..||  ::::||.||||.||:..:.|....||   ||.|:
Zfish   446 FLAEMFKYLFLLFAEEEDLPFNVEDYVFTTEAHLLPLSLSTASNSPAP---PVINS 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ia	NP_727408.2	LanC_like	216..664	CDD:471159	149/490 (30%)
edem3	XP_005166989.2	Glyco_hydro_47	44..482	CDD:460241	147/484 (30%)
		PA_EDEM3_like	644..770	CDD:239041