Protein Alignment alpha-Man-Ia and edem1

DIOPT Version :10

• Sequence 1: NP_727408.2
• Gene: alpha-Man-Ia / 31957
• FlyBaseID: FBgn0259170
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_989397.2
• Gene: edem1 / 395034
• XenbaseID: XB-GENE-492908
• Length: 619
• Species: Xenopus tropicalis
• Alignment Length: 589
• Identity: 168/589 - (28%)
• Similarity: 259/589 - (43%)
• Gaps: 120/589 - (20%)

  Fly   139 GSSSTGPR---------ILQAAEALMEGNVDSISLPAAAPLTAATTSSAKSLENSQGSDTPHSHA 194
            ||...|.|         :|:.....:.|    :.||..:|:.                 .|..||
 Frog    20 GSGGPGMRWCSVLLGLLLLRLGLHALRG----LILPGTSPVV-----------------VPGVHA 63

  Fly   195 --NTTNADITMGIADHN-------PGGIQFERRAHVKQMMEHAWHNYKLYAWGKNELRPLSQR-- 248
              ..:.....:|..|..       |.|::.|.|...:.|....:.:|..||:.::||.|:..|
 Frog    64 VCRASYGRFVLGAGDEYGRRYSSFPEGLRKEMREMARGMFSFGYDSYMKYAFPEDELNPILCRGR 128

  Fly   249 ------PHSASI---FGSYDLGATIVDGLDTLYIMGLEKEYREGRDWIERKFSLDNISAELSVFE 304
                  |.:.:|   .|:|.|  |::|.||||.:||...|:......:....|.|. ::.:.|||
 Frog   129 GPDHGDPSNLNINDVLGNYSL--TLIDALDTLAVMGNATEFHRAVRLVIDTVSFDK-NSTVQVFE 190

  Fly   305 TNIRFVG----------------GMLTLYAFTGDPLYKEKAQHVADKLLPAFQ-TPTGIPYALVN 352
            ..||.:|                |.:||..:..:.|:  .|:.:|.:|||||: |.||:||..||
 Frog   191 ATIRILGSLLSAHIILTDSKQPFGNMTLSGYDNELLH--MARDLAVRLLPAFENTKTGMPYPRVN 253

  Fly   353 TKTGV---AKNYGWASGGSSILSEFGTLHLEFAYLSDITGNPLYRERVQTIRQVLKEIEKPKGLY 414
            .|.||   ::|....:|..|:|.|||.|.   ..|.|.|...:.|..|:.:..:.   ....||.
 Frog   254 LKKGVPPDSRNETCTAGAGSLLVEFGILS---RLLGDSTFEWVARRAVRALWSLR---SNDTGLL 312

  Fly   415 PNFLNPKTGKWGQLHMSLGALGDSYYEYLLKAWLQSGQTDEEAREMFDEAMLAILDKMVR----- 474
            .|.:|.:||:|......|||..||::|||||:.:..|  :||..|||:||..:|.:.:.|
 Frog   313 GNVVNIQTGQWVGKQSGLGAGLDSFFEYLLKSHILFG--EEEDLEMFNEAYKSIQNHLRRGREAC 375

  Fly   475 ----TSPGGLTYVSDLKFDRLEHKMDHLACFSGGLFALGAATRQNDYTDKYMEVGKGITNTC-HE 534
                ..|.....|:.|....:...:|.|..|..||..|     :.|..|.          .| |.
 Frog   376 NEGEGDPPLYVNVNMLNGQLMNTWIDSLQAFFPGLQVL-----KGDIEDA----------ICLHA 425

  Fly   535 SYIRAPTQLGPEAFRFSEAVEARALRSQEKYYILRPETFESYFVLWRLTHDQKYRDWGWEAVLAL 599
            .|.....:.|....|::..::|    ....:|.||||..||.::|::.|.:..|...|.:.:|:|
 Frog   426 FYYAIWKRYGALPERYNWQLQA----PDVSFYPLRPELVESTYLLYQATKNPFYLHVGMDILLSL 486

  Fly   600 EKHCRTAHGYCGLRNVYQQEPQKDDVQQSFFLAETLKYLYLLFSDDSVLPL----DEWVFNTEAH 660
            |||.:...||..|.:|.  :..::|..:||||:||.|||||||.:|:  ||    ::::|.||.|
 Frog   487 EKHAKAKCGYATLHHVV--DKSQEDRMESFFLSETCKYLYLLFDEDN--PLHRVDNKYLFTTEGH 547

  Fly   661 PLPI 664
            .:|:
 Frog   548 LIPL 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ia	NP_727408.2	LanC_like	216..664	CDD:471159	151/492 (31%)
edem1	NP_989397.2	Glyco_hydro_47	102..551	CDD:460241	149/484 (31%)