Protein Alignment alpha-Man-Ia and edem1

DIOPT Version :10

• Sequence 1: NP_727408.2
• Gene: alpha-Man-Ia / 31957
• FlyBaseID: FBgn0259170
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_957483.2
• Gene: edem1 / 394164
• ZFINID: ZDB-GENE-040426-808
• Length: 628
• Species: Danio rerio
• Alignment Length: 504
• Identity: 150/504 - (29%)
• Similarity: 233/504 - (46%)
• Gaps: 89/504 - (17%)

  Fly   210 PGGIQFERRAHVKQMMEHAWHNYKLYAWGKNELRPLS--------QRPHSASI---FGSYDLGAT 263
            |..::.:.||..:.|....:.||..:|:.::||.|::        ..|.:.:|   .|:|.|  |
Zfish   108 PDALKVKMRAMARDMFYFGYDNYMKFAFPEDELNPIACEGRGPDVLNPSNININDVLGNYSL--T 170

  Fly   264 IVDGLDTLYIMGLEKEYREGRDWIERKFSLDNIS----AELSVFETNIRFVGGMLTLYAFTGDPL 324
            ::|.||||.::|...|:...     .|..:|.:|    :.:.|||.|||.:|.:::.:....||.
Zfish   171 LIDTLDTLLVLGNVTEFHRA-----VKLVIDTVSFDKDSTVQVFEANIRILGSLISAHILLTDPR 230

  Fly   325 ----------YKEKAQHVAD----KLLPAFQ-TPTGIPYALVNTKTGV---AKNYGWASGGSSIL 371
                      |..:..|:|.    :|||||: |.|||||..||.|.||   :.|....:|..|:|
Zfish   231 HPFGDVGLKDYDNELLHLAHDLAVRLLPAFENTSTGIPYPRVNLKNGVPPDSINETCTAGAGSLL 295

  Fly   372 SEFGTLHLEFAYLSDITGNPLYRERVQTIRQVLKEIEKPK----GLYPNFLNPKTGKWGQLHMSL 432
            .|||       .||.:.|:..:.   ...|:.:|.:.|.:    ||..|.:|.:||:|......|
Zfish   296 VEFG-------ILSRLIGDSTFE---WVARRAVKALWKLRSNETGLLGNVVNIQTGQWVGKQSGL 350

  Fly   433 GALGDSYYEYLLKAWLQSGQTDEEAREMFDEAMLAILDKMVR---------TSPGGLTYVSDLKF 488
            ||..||:||||||:::..|  ::|...||..|..:|...:.|         ..|.....|:....
Zfish   351 GAGMDSFYEYLLKSYILFG--EKEDFRMFTAAYESIQSHLRRGREACNEGEGDPPLYVNVNMFNG 413

  Fly   489 DRLEHKMDHLACFSGGLFALGAATRQNDYTDKYMEVGKGITNTC-HESYIRAPTQLGPEAFRFSE 552
            ..:...:|.|..|..||..|..            :|...|   | |..|.....:.|....|::.
Zfish   414 QIMNTWIDSLQAFFPGLQVLNG------------DVENAI---CLHAFYYAIWKRFGALPERYNW 463

  Fly   553 AVEARALRSQEKYYILRPETFESYFVLWRLTHDQKYRDWGWEAVLALEKHCRTAHGYCGLRNVYQ 617
            .::|    ....:|.||||..||.::|::.|.:..|...|.:.:.:|||:.:...||..|.:|.
Zfish   464 QLQA----PDVLFYPLRPELVESTYLLYQATKNPFYLHVGMDILESLEKNTKVRCGYATLHHVV- 523

  Fly   618 QEPQKDDVQQSFFLAETLKYLYLLFSDDSVLPLDE--WVFNTEAHPLPI 664
             :..|:|..:||||:||.|||||||.:|:.|...|  ::|.||.|.:||
Zfish   524 -DKSKEDRMESFFLSETCKYLYLLFDEDNPLHKSENKYIFTTEGHVVPI 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ia	NP_727408.2	LanC_like	216..664	CDD:471159	147/496 (30%)
edem1	NP_957483.2	Glyco_hydro_47	122..571	CDD:460241	145/488 (30%)