Protein Alignment alpha-Man-Ia and Man1c1

DIOPT Version :10

• Sequence 1: NP_727408.2
• Gene: alpha-Man-Ia / 31957
• FlyBaseID: FBgn0259170
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_063144134.1
• Gene: Man1c1 / 362625
• RGDID: 1309672
• Length: 655
• Species: Rattus norvegicus
• Alignment Length: 633
• Identity: 280/633 - (44%)
• Similarity: 379/633 - (59%)
• Gaps: 86/633 - (13%)

  Fly    93 HPKNLQRQLQQQQQQQLQQQQPN-KIVIEIG-----LSNDSGPSSAPASSTLGSSS--------- 142
            |...|:|.....     :.|||. :::.||.     ...:..|:.|||:...|...
  Rat    45 HSSRLKRLFSAS-----RTQQPGLEVMAEIAGHHSVSEQEPPPNPAPAAPAPGEDDSGRLVGVLR 104

  Fly   143 ----------TGPRILQAAEALMEGNVDSISLPAAAPLTAATTSSAKSLENSQGSDTPHSHANTT 197
                      ||||        .|||    .:.|..|...:...|..  .||..|...|....|.
  Rat   105 RKGWLRRTRPTGPR--------EEGN----RVSALRPQEESVRFSFD--YNSFRSRLRHPVLGTR 155

  Fly   198 NADITMGIADHNPGGIQFERRAHVKQMMEHAWHNYKLYAWGKNELRPLSQRPHSASIFGSYDLGA 262
            ..:      ......:...:|..:|:||..:|.:|:.||.||||||||::.....|:||... ||
  Rat   156 TDE------SQESQSLVRAQREKIKEMMRFSWQSYRRYAMGKNELRPLTKDGFEGSMFGGLS-GA 213

  Fly   263 TIVDGLDTLYIMGLEKEYREGRDWIERKFSLDNISAELSVFETNIRFVGGMLTLYAFTGDPLYKE 327
            ||:|.|||||:|.|::|::|.:.|::..|.| |:|.|.|:||.|||::||:|:.:..||:.:::.
  Rat   214 TIIDSLDTLYLMELKEEFQEAKAWVQDSFHL-NVSGEASLFEVNIRYIGGLLSAFYLTGEEVFRV 277

  Fly   328 KAQHVADKLLPAFQTPTGIPYALVNTKTGVAKNYGWA-SGGSSILSEFGTLHLEFAYLSDITGNP 391
            ||..:.:||||||.||||||..:||.|:|   ::||| :|.||||:|||:|||||.:|::::|||
  Rat   278 KAIKLGEKLLPAFNTPTGIPKGVVNFKSG---SWGWATAGSSSILAEFGSLHLEFLHLTELSGNP 339

  Fly   392 LYRE------------------------------RVQTIRQVLKEIEKPKGLYPNFLNPKTGKWG 426
            ::.|                              ||:.||:||:||:||.|||||||:|.:|.|.
  Rat   340 IFAEKVLSGSCWQQAGGRLAELIPRHCSWLPKATRVRNIRKVLREIDKPFGLYPNFLSPVSGNWV 404

  Fly   427 QLHMSLGALGDSYYEYLLKAWLQSGQTDEEAREMFDEAMLAILDKMVRTSPGGLTYVSDLKFDRL 491
            |.|:|:|.||||:||||:|:||.|.:||.||:.|:.||:.||...:|..|||||||:::.:...|
  Rat   405 QHHVSVGGLGDSFYEYLIKSWLMSAKTDMEAKTMYYEALEAIETYLVNVSPGGLTYIAEWRGGIL 469

  Fly   492 EHKMDHLACFSGGLFALGAATRQNDYTDKYMEVGKGITNTCHESYIRAPTQLGPEAFRFSEAVEA 556
            :|||.||||||||:.||||...:.|....|.|:...||.||||||.|:.|:||||||.|:...||
  Rat   470 DHKMGHLACFSGGMIALGAEDAKEDKRAYYRELAAQITRTCHESYARSDTKLGPEAFWFNSGREA 534

  Fly   557 RALRSQEKYYILRPETFESYFVLWRLTHDQKYRDWGWEAVLALEKHCRTAHGYCGLRNVYQQEPQ 621
            .|.:..|.|||||||..|||..|||.|||..||:||||.|:||||||||..|:.|:::||...|.
  Rat   535 VATQLSESYYILRPEVVESYMYLWRQTHDPIYREWGWEVVMALEKHCRTEGGFSGIQDVYSSNPN 599

  Fly   622 KDDVQQSFFLAETLKYLYLLFSDDSVLPLDEWVFNTEAHPLPIKGANA 669
            .|:.||||||||||||||||||:|.||.|::|||||||||||:..:::
  Rat   600 HDNRQQSFFLAETLKYLYLLFSEDDVLSLEDWVFNTEAHPLPVNRSDS 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ia	NP_727408.2	LanC_like	216..664	CDD:471159	251/478 (53%)
Man1c1	XP_063144134.1	None