Protein Alignment alpha-Man-Ia and Edem2

DIOPT Version :10

• Sequence 1: NP_727408.2
• Gene: alpha-Man-Ia / 31957
• FlyBaseID: FBgn0259170
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001004230.1
• Gene: Edem2 / 296304
• RGDID: 1303074
• Length: 576
• Species: Rattus norvegicus
• Alignment Length: 494
• Identity: 161/494 - (32%)
• Similarity: 230/494 - (46%)
• Gaps: 98/494 - (19%)

  Fly   218 RAHVKQMMEHAWHNYKLYAWGKNELRPLSQRPHSASIFGSYDLGATIVDGLDTLYIMGLEKEYRE 282
            |..||.|..||:.:|...|:..:|||||:...|..  :||:.|  |::|.||||.|:|...|::.
  Rat    36 RERVKAMFYHAYDSYLENAFPYDELRPLTCDGHDT--WGSFSL--TLIDALDTLLILGNTSEFQR 96

  Fly   283 GRDWIERKFSLDNISAELSVFETNIRFVGGMLTLYAFT-------------GDPLYKEKAQHVAD 334
            ..:.::.....| |....||||||||.|||:|:.:..:             ..||.: .|:..|.
  Rat    97 VVEVLQDNVDFD-IDVNASVFETNIRVVGGLLSAHLLSKKAGVEVEAGWPCSGPLLR-MAEEAAR 159

  Fly   335 KLLPAFQTPTGIPYALVNTKTGVAKNYGWASGGSSILSEFGTLHLEFAYLSDITGNPLYRERVQT 399
            |||||||||||:||..||...||  |.|  ....:..:..||..:|||.||.:||:|::.:..:.
  Rat   160 KLLPAFQTPTGMPYGTVNLLHGV--NPG--ETPVTCTAGIGTFIVEFATLSSLTGDPVFEDVARV 220

  Fly   400 IRQVLKEIEKPKGLYPNFLNPKTGKWGQLHMSLGALGDSYYEYLLKA--WLQSGQTDEEAREMFD 462
            ....|.|.....||..|.::..||||......:||..|||:|||:|.  .||    |::...||.
  Rat   221 ALMRLWESRSDIGLVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKGAILLQ----DKKLMAMFL 281

  Fly   463 EAMLAILD-----------KMVRTSPGGLTYVSDLKFDRLEHKMDHLACFSGGLFALGAATRQND 516
            |...||.:           :|.:.:      ||...|..||.....|....|.:
  Rat   282 EYNKAIRNYTHFDDWYLWVQMYKGT------VSMPVFQSLEAYWPGLQSLIGDI----------- 329

  Fly   517 YTDKYMEVGKGITNTCHESYIRAPTQLG--PEAFRFSE--AVEARALRSQEKYYILRPETFESYF 577
              |..|..        ..:|.....|.|  ||.:...:  .||.|      :.|.||||..||..
  Rat   330 --DNAMRT--------FLNYYTVWKQFGGLPEFYNIPQGYTVEKR------EGYPLRPELIESAM 378

  Fly   578 VLWRLTHDQKYRDWGWEAVLALEKHCRTAHGYCGLRNVYQQEPQKDDVQQSFFLAETLKYLYLLF 642
            .|:|.|.|....:.|.:||.::||..:...|:..::::  ::.:.|:..:|||||||:|||||||
  Rat   379 YLYRATGDPTLLELGRDAVESIEKISKVECGFATIKDL--RDHKLDNRMESFFLAETVKYLYLLF 441

  Fly   643 -----------SDDSVL-PLDE-------WVFNTEAHPL 662
                       :.|||: |..|       ::|||||||:
  Rat   442 HPNNFIHNNGSTFDSVMTPHGECILGAGGYIFNTEAHPI 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ia	NP_727408.2	LanC_like	216..664	CDD:471159	161/494 (33%)
Edem2	NP_001004230.1	Glyco_hydro_47	42..480	CDD:460241	157/486 (32%)