Protein Alignment alpha-Man-Ia and Man1a2

DIOPT Version :10

• Sequence 1: NP_727408.2
• Gene: alpha-Man-Ia / 31957
• FlyBaseID: FBgn0259170
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001099922.1
• Gene: Man1a2 / 295319
• RGDID: 1309767
• Length: 641
• Species: Rattus norvegicus
• Alignment Length: 478
• Identity: 273/478 - (57%)
• Similarity: 359/478 - (75%)
• Gaps: 10/478 - (2%)

  Fly   203 MGIADHNPGGIQF-ERRAHVKQMMEHAWHNYKLYAWGKNELRPLSQRPHSASIFGSYDLGATIVD 266
            :|::..:|...:. ::|..:|:||:|||.||:.|.||.|||||::::.||.:||||..:||||||
  Rat   165 VGVSGGDPEDAEIRKKRDKIKEMMKHAWDNYRTYGWGHNELRPIARKGHSTNIFGSSQMGATIVD 229

  Fly   267 GLDTLYIMGLEKEYREGRDWIERKFSLD-NISAELSVFETNIRFVGGMLTLYAFTGDPLYKEKAQ 330
            .|||||||||..|:.:|:.|||.  :|| ::::|:||||.||||:||:|..|..:|:.::|.||.
  Rat   230 ALDTLYIMGLHDEFMDGQRWIED--NLDFSVNSEVSVFEVNIRFIGGLLAAYYLSGEEIFKTKAV 292

  Fly   331 HVADKLLPAFQTPTGIPYALVNTKTGVAKNYGWASGGSSILSEFGTLHLEFAYLSDITGNPLYRE 395
            .:|:||||||.||||||:|:||.|:||.:|:||||.|||||:||||||:||.:||.:||:..|..
  Rat   293 QLAEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFVHLSYLTGDLTYYN 357

  Fly   396 RVQTIRQVLKEIEKPKGLYPNFLNPKTGKWGQLHMSLGALGDSYYEYLLKAWLQSGQTDEEAREM 460
            :|..||::|:::|:|.|||||:|||:||:|||.|.|:|.||||:|||||||||.|.:||.|||.|
  Rat   358 KVMHIRKLLQKMERPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAWLMSDKTDHEARRM 422

  Fly   461 FDEAMLAILDKMVRTSPGGLTYVSDLKFDRLEHKMDHLACFSGGLFALGAATRQNDYTDKYMEVG 525
            :|:|:.||...:::.|.|||.::.:.|...||.||.|||||:||:|||||...:.|....|:|:|
  Rat   423 YDDAVEAIEKHLIKKSRGGLVFIGEWKNGHLERKMGHLACFAGGMFALGADGSRKDKAGHYLELG 487

  Fly   526 KGITNTCHESYIRAPTQLGPEAFRFSEAVEARALRSQEKYYILRPETFESYFVLWRLTHDQKYRD 590
            ..|..||||||.|...:||||:|:|..||||.|:|..|||||||||..|:|:.|||.|||.:||.
  Rat   488 AEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQ 552

  Fly   591 WGWEAVLALEKHCRTAHGYCGLRNVYQQEPQKDDVQQSFFLAETLKYLYLLFSDDSVLPLDEWVF 655
            |||||.||:||.||.:.|:.|:::||...|..|||||||||||||||||||||.|.:||||.|||
  Rat   553 WGWEAALAIEKSCRVSGGFSGVKDVYSPTPAHDDVQQSFFLAETLKYLYLLFSGDDLLPLDHWVF 617

  Fly   656 NTEAHPLPIKGANAYYRQAPVTL 678
            ||||||||:      .|.|..||
  Rat   618 NTEAHPLPV------LRLANTTL 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ia	NP_727408.2	LanC_like	216..664	CDD:471159	266/448 (59%)
Man1a2	NP_001099922.1	PTZ00121	<109..208	CDD:173412	18/42 (43%)
		Glyco_hydro_47	187..626	CDD:460241	264/440 (60%)