Protein Alignment alpha-Man-Ia and mnl1

DIOPT Version :10

• Sequence 1: NP_727408.2
• Gene: alpha-Man-Ia / 31957
• FlyBaseID: FBgn0259170
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_594434.1
• Gene: mnl1 / 2541981
• PomBaseID: SPAC23A1.04C
• Length: 787
• Species: Schizosaccharomyces pombe
• Alignment Length: 498
• Identity: 136/498 - (27%)
• Similarity: 229/498 - (45%)
• Gaps: 103/498 - (20%)

  Fly   216 ERRAHVKQMMEHAWHNYKLYAWGKNELRPLS--------QRPHSA---SIFGSYDLGATIVDGLD 269
            |.|...:::..|.::||..:|:..:||.|||        :.|::.   .:.|.|.|  |:||.||
pombe    34 ELRETSRRLFYHGYNNYMQFAFPNDELAPLSCEGLGPDYENPNNIGVNDVRGDYLL--TLVDVLD 96

  Fly   270 TLYIMGLEKEYREGRDWIERKFSLDNISAELSVFETNIRFVGGMLTLYAFTGD-------PLYKE 327
            ||.::|..:.:::..|.:....:.:. ..::.|||..||.:||:|:.:.|..:       ||||.
pombe    97 TLVVLGDREGFQDAVDKVIHHINFER-DTKVQVFEATIRILGGLLSSHIFASEEKYGFQIPLYKG 160

  Fly   328 K----AQHVADKLLPAFQTPTGIPYALVNTKTGVA---KNYGWASGGSSILSEFGTLHLEFAYLS 385
            :    |..:|::|||||:||||||:|.:|...|||   .....|:..||::       |||:.|:
pombe   161 ELLTLATELAERLLPAFRTPTGIPFARINLMKGVAYREVTENCAAAASSLV-------LEFSMLT 218

  Fly   386 DITGNPLYRERVQTIRQVLKEIEKPKGLYPNFLNPKTGKWGQLHMSLGALGDSYYEYLLKAWLQS 450
            .:|||..::...:.....:.:.....||..|.::..:|:|......:||..||:|||..|:::..
pombe   219 ALTGNNKFKASAENAFFSVWKRRSGIGLLGNSIDVLSGRWIYPVSGVGAGIDSFYEYAFKSYIFL 283

  Fly   451 GQTDEEAREMFDEAMLAILDKMVRT-----------------SPGGLTYVSDLKFDRLEHKMDHL 498
            |          |...|.:..|.:.:                 |..|:.         :...:|.|
pombe   284 G----------DPRYLEVWQKSLESLRHYTASLNEYYYQNVYSANGMV---------MSRWVDSL 329

  Fly   499 ACFSGGLFALGAATRQNDYTDKYMEVGKGITNTCHESYIRAPTQLG--PEAFR-FSEAVEARALR 560
            :.:..||..|...          :|:.|.:    |..|.....:.|  ||.:. :::::|...
pombe   330 SAYFPGLLVLAGE----------LELAKKM----HLYYFSIYLKFGQLPERYNLYTKSIELNG-- 378

  Fly   561 SQEKYYILRPETFESYFVLWRLTHDQKYRDWGWEAVLALEKHCRTAHGYCGLRNVYQQEPQKDDV 625
                 |.||||..||.:.|:|.|.|..|...|...:..:|.|..|..|:..:.|:  ::....:.
pombe   379 -----YPLRPEFAESTYYLYRATKDVFYLHVGELLLSNIENHLWTPCGFAAVENL--EKYTLSNR 436

  Fly   626 QQSFFLAETLKYLYLLFSDDSVLPL----DEWVFNTEAHPLPI 664
            .:||||:||||||:|||.||:  |:    .:::|.||.|..|:
pombe   437 MESFFLSETLKYLFLLFDDDN--PIHRSHHDFIFTTEGHLFPV 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ia	NP_727408.2	LanC_like	216..664	CDD:471159	135/496 (27%)
mnl1	NP_594434.1	Glyco_hydro_47	42..477	CDD:460241	133/488 (27%)