Protein Alignment alpha-Man-Ia and Man1b1

DIOPT Version :10

• Sequence 1: NP_727408.2
• Gene: alpha-Man-Ia / 31957
• FlyBaseID: FBgn0259170
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001025154.1
• Gene: Man1b1 / 227619
• MGIID: 2684954
• Length: 658
• Species: Mus musculus
• Alignment Length: 586
• Identity: 202/586 - (34%)
• Similarity: 315/586 - (53%)
• Gaps: 65/586 - (11%)

  Fly   101 LQQQQQQQLQ------QQQPNKIVIEIGLSNDSGPSSAPASSTLGSSSTGPRILQAAEALMEGNV 159
            |.|::|:..:      |.:|...|.:.|:.:|:....|    .||            :|..|.|
Mouse   112 LSQKRQRHFRRGPPHLQIRPPNTVSKDGMQDDAKEREA----ALG------------KAQQEEN- 159

  Fly   160 DSISLPAAAPLTAATTSSAKS--LENSQGSDTPHSHANTTNADITMGIADHNPGGIQFERRAHVK 222
                       |..|..|.:.  :|..|.::.|:..|..:...:.:............||:..|.
Mouse   160 -----------TQRTVISWRGAVIEPEQATELPYKRAEASIKPLVLASKIWKEPAPPNERQKGVI 213

  Fly   223 QMMEHAWHNYKLYAWGKNELRPLSQRPHSASIFGSYDLGATIVDGLDTLYIMGLEKEYREGRDWI 287
            :...|||..|:.:|||.:||:|:|:.  .:..||   ||.|::|.|||::|:||::|:::.|.|:
Mouse   214 EAFLHAWKGYQKFAWGHDELKPVSKT--FSEWFG---LGLTLIDALDTMWILGLKQEFKQARKWV 273

  Fly   288 ERKFSLDNISAELSVFETNIRFVGGMLTLYAFTGDPLYKEKAQHVADKLLPAFQTPTGIPYALVN 352
            ........ :.::::||:.||.:||:|:.|..:||.|:..||:....:|:|||.||:.|||:.||
Mouse   274 SENLDFQK-NVDVNLFESTIRILGGLLSTYHLSGDSLFLTKAEDFGKRLMPAFTTPSKIPYSDVN 337

  Fly   353 TKTGVAKNYGWASGGSSILSEFGTLHLEFAYLSDITGNPLYRERVQTIRQVLKEIE-KPKGLYPN 416
            ..||.|.:..|.|  .|.::|..::.|||..||.:||...::|.|:.:.:.:..:. |..||.|.
Mouse   338 IGTGFAHSPQWTS--DSTVAEVTSIQLEFRELSRLTGIKKFQEAVEEVTKHIHSLSGKKDGLVPM 400

  Fly   417 FLNPKTGKWGQLH---MSLGALGDSYYEYLLKAWLQSGQTDEEAREMFDEAMLAILDKMVRTS-P 477
            |:|..:|.:  .|   .:|||..|||||||||.|:|.|:.:.:..|.:.:|:..|...::|.| |
Mouse   401 FINTNSGLF--THPGVFTLGARADSYYEYLLKQWIQGGKKETQLLEDYVKAIEGIKAHLLRQSQP 463

  Fly   478 GGLTYVSDLKFDRLEHKMDHLACFSGGLFALGAATRQNDYTDKYMEVGKGITNTCHESYIRAPTQ 542
            ..||:|.:|...|...|||||.||..|..|||.   .:.....:|::.:.:..||::...:..|.
Mouse   464 RKLTFVGELAHGRFSAKMDHLVCFLPGTLALGV---HHGLPADHMDLARALMETCYQMNQQMETG 525

  Fly   543 LGPEAFRFSEAVEARA------LRSQEKYYILRPETFESYFVLWRLTHDQKYRDWGWEAVLALEK 601
            |.||...|:  :..||      ::..:::.:|||||.||.|.|:|:|.|:||:|||||.:.:..|
Mouse   526 LSPEIAHFN--MYPRADHKDVEVKPADRHNLLRPETVESLFYLYRVTRDRKYQDWGWEILQSFNK 588

  Fly   602 HCRT-AHGYCGLRNVY-QQEPQKDDVQQSFFLAETLKYLYLLFSDD-SVLPLDEWVFNTEAHPLP 663
            :.|. :.||..:.||. ..:|:..|..:|||:.||||||||||||| .:|.||..||||||||||
Mouse   589 YTRVPSGGYSSINNVQNSHKPEPRDKMESFFVGETLKYLYLLFSDDLELLSLDSCVFNTEAHPLP 653

  Fly   664 I 664
            |
Mouse   654 I 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ia	NP_727408.2	LanC_like	216..664	CDD:471159	179/461 (39%)
Man1b1	NP_001025154.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	123..142		4/18 (22%)
		Glyco_hydro_47	215..654	CDD:460241	176/453 (39%)